DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NetA and Ushbp1

DIOPT Version :9

Sequence 1:	NP_001285243.1	Gene:	NetA / 32398	FlyBaseID:	FBgn0015773	Length:	726	Species:	Drosophila melanogaster
Sequence 2:	NP_852083.2	Gene:	Ushbp1 / 234395	MGIID:	1922920	Length:	680	Species:	Mus musculus

Alignment Length:	236	Identity:	46/236 - (19%)
Similarity:	72/236 - (30%)	Gaps:	64/236 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   417 RDATKPLTHRK------------VCKACDCHPIGSSGKICNSTSGQC-------------PCKDG 456
            |..|||..|::            :.:.||   :||...:..|...||             |...|
Mouse    37 RFETKPELHQEYLGPGLQSPRNWIKEGCD---VGSHAVLSLSPEEQCEPEVEAHQVLQEAPLDSG 98

  Fly   457 VTGLTCNRCARGYQ---QSRSHIAPCIKQPPRMINMLDTQNTAPEPDEPESSPGSGGDRNGAAGM 518
            ...::........|   .|...:...::.     :.|....:....|..:.:||..||....||.
Mouse    99 PAEISVPSVYETLQCRLSSLEAVVAALRH-----HSLSFPKSVEAEDRDQGAPGPFGDEKEDAGP 158

  Fly   519 AAQSQYYRTEGGRECGKCRVSTKRLNLNKFCKRDYAI---MAKVIGRDTSSEAVSREVQRRAMDP 580
            ..|......|        |.:..||.|   |.|:..:   .|.:.......|.:.|:||
Mouse   159 GQQEAARLIE--------RNAWLRLAL---CNREDELACTQASLQDAQAEKETLQRQVQ------ 206

  Fly   581 DVADYEMDQVQPGSARSPITGVYEFQAADYPNPNPNPRGSE 621
                 |::........||.|.:..   |...|.|.:..|:|
Mouse   207 -----ELEDSLMQMEASPPTPILR---AGRRNSNSSTSGAE 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NetA	NP_001285243.1	LamNT	44..280	CDD:214532
		EGF_Lam	312..357	CDD:238012
		EGF_Lam	369..426	CDD:238012	4/8 (50%)
		EGF_Lam	431..479	CDD:238012	11/63 (17%)
		NTR_netrin-1_like	545..723	CDD:239634	17/80 (21%)
Ushbp1	NP_852083.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..51		5/13 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	134..161		7/26 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	220..247		6/23 (26%)
		MCC-bdg_PDZ	288..352	CDD:287477
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	384..405
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	524..549
		BAR	<585..>655	CDD:299863
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3512
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900