DRSC/TRiP Functional Genomics Resources

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Protein Alignment NetA and MEGF9

DIOPT Version :9

Sequence 1:NP_001285243.1 Gene:NetA / 32398 FlyBaseID:FBgn0015773 Length:726 Species:Drosophila melanogaster
Sequence 2:NP_001073966.2 Gene:MEGF9 / 1955 HGNCID:3234 Length:602 Species:Homo sapiens


Alignment Length:375 Identity:88/375 - (23%)
Similarity:114/375 - (30%) Gaps:144/375 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly   204 VTRPLVSRIAFSTLEGRPSSRDLDSSPVLQDWVTATDIRVVFHRLQRPDP-------------QA 255
            |.|||.:.....:.|..|.            |.||......|.....|.|             ||
Human    87 VHRPLAATSPAQSPETTPL------------WATAGPSSTTFQAPLGPSPTTPPAAERTSTTSQA 139

  Fly   256 -------LLSLEAGGA-------------------TDLASGKYSVPLANGPAGNNIEANLGGDVA 294
                   .||...|.|                   .||.|...|..|...||..          |
Human   140 PTRPAPTTLSTTTGPAPTTPVATTVPAPTTPRTPTPDLPSSSNSSVLPTPPATE----------A 194

  Fly   295 TSGSGLHYAISDFSVG-----------GRCKC---------------------NGHASKCSTDAS 327
            .|.....|..:...||           |:|:|                     :|....|.....
Human   195 PSSPPPEYVCNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPH 259

  Fly   328 GQLN--------CECSHNTAGRDCERCKPFHFDRPWARATAKEANECKECNCNKHARQCRFNMEI 384
            |.|:        |:|.....|..|:||:..::        ....|.|..|.||..:..|      
Human   260 GALSIPCNSSGKCQCKVGVIGSICDRCQDGYY--------GFSKNGCLPCQCNNRSASC------ 310

  Fly   385 FRLSQGVSGGVCQNCRHSTTGRNCHQCKEGFYR--DATKPLTHRKVCKACDCHPIGSSGKICNST 447
                 ....|.|.||:.::.|.:|.:||||||:  ||||.      |..|.|..:.|:|. |:..
Human   311 -----DALTGACLNCQENSKGNHCEECKEGFYQSPDATKE------CLRCPCSAVTSTGS-CSIK 363

  Fly   448 SG----QC-PCKDGVTGLTCNRCARGYQ---------QSRSHIAPCIKQP 483
            |.    :| .||||..|..||:|..||.         |...|:.| :|.|
Human   364 SSELEPECDQCKDGYIGPNCNKCENGYYNFDSICRKCQCHGHVDP-VKTP 412

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NetANP_001285243.1 LamNT 44..280 CDD:214532 23/114 (20%)
EGF_Lam 312..357 CDD:238012 12/73 (16%)
EGF_Lam 369..426 CDD:238012 20/58 (34%)
EGF_Lam 431..479 CDD:238012 19/61 (31%)
NTR_netrin-1_like 545..723 CDD:239634
MEGF9NP_001073966.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 38..199 27/133 (20%)
EGF_Lam 204..252 CDD:238012 6/47 (13%)
Laminin_EGF 254..301 CDD:278482 11/54 (20%)
EGF_Lam 300..346 CDD:238012 20/62 (32%)
EGF_Lam <373..401 CDD:238012 10/27 (37%)
Laminin_EGF 400..>441 CDD:278482 5/14 (36%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.000

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