Protein Alignment sbm and GAP1

DIOPT Version :10

• Sequence 1: NP_727785.1
• Gene: sbm / 32397
• FlyBaseID: FBgn0030574
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_012965.3
• Gene: GAP1 / 853912
• SGDID: S000001747
• Length: 602
• Species: Saccharomyces cerevisiae
• Alignment Length: 568
• Identity: 125/568 - (22%)
• Similarity: 223/568 - (39%)
• Gaps: 109/568 - (19%)

  Fly    17 KNNSTDNNRGHNVPT-----KTTSNGTMCANGSLGTEGPEAPETDSSGTG----------RMRKP 66
            |||  .:|..||..|     .|....|:.:|||       |...|.:|:|          :..||
Yeast     9 KNN--PDNLKHNGITIDSEFLTQEPITIPSNGS-------AVSIDETGSGSKWQDFKDSFKRVKP 64

  Fly    67 LE--RNGSTQNHVV----------HLE-RRLGLFSGVALIVGTMIGSGIFVSPSGLLVRTGSVGV 118
            :|  .|.|....|.          ||: |.|.:     :.:|..||:|:.|. ||..:|||....
Yeast    65 IEVDPNLSEAEKVAIITAQTPLKHHLKNRHLQM-----IAIGGAIGTGLLVG-SGTALRTGGPAS 123

  Fly   119 SFIIWLACGVLSLLGALAYAELGTMNTSSGAEWAY---FMD-AYGPAPAF--LFSWVSTLVLKPS 177
            ..|.|.:.|.:.....:|..||..:...||....|   |:| ::|.|..|  :..|:..|.|:
Yeast   124 LLIGWGSTGTMIYAMVMALGELAVIFPISGGFTTYATRFIDESFGYANNFNYMLQWLVVLPLE-- 186

  Fly   178 QMAIICLSFAQYAVEAFVTECDPPRGVVKMVALVAIVMILFVNCYSVNLGMAVQNVFTAAKLVAV 242
                  :..|...|..:.|:   |:.....|||..:.::: :|.:.|......:.||:..|::.|
Yeast   187 ------IVSASITVNFWGTD---PKYRDGFVALFWLAIVI-INMFGVKGYGEAEFVFSFIKVITV 241

  Fly   243 V-------VVICGG--AWKLMQGNTQHLSNAFNGPMPNVGA----IATAFYTGLWAYDGWNNLNY 294
            |       ::.|||  ....:.|...|...||.|..|  ||    :.:.|.|..:::.|...:..
Yeast   242 VGFIILGIILNCGGGPTGGYIGGKYWHDPGAFAGDTP--GAKFKGVCSVFVTAAFSFAGSELVGL 304

  Fly   295 VTEEIKNPSKNLPRSIIIGIPLVTLCY--ALINISYLAAMSPQEMIESEAV-------AVTFGNR 350
            ...|...|.|::|::.......:||.|  :|:.|..|...:.:.:|.:.:|       .:.....
Yeast   305 AASESVEPRKSVPKAAKQVFWRITLFYILSLLMIGLLVPYNDKSLIGASSVDAAASPFVIAIKTH 369

  Fly   351 ILGALAWLMPLSVTISTFGSANGTLFAAGRLCFAASREGHLLDILSYVHVR-------RLTPAPG 408
            .:..|..::.:.:.|:.....|..::|..|...|.:.:..|.:|.|||..:       .:|.|.|
Yeast   370 GIKGLPSVVNVVILIAVLSVGNSAIYACSRTMVALAEQRFLPEIFSYVDRKGRPLVGIAVTSAFG 434

  Fly   409 LIFHSLIASAMVLHGTIDSLIDFFSFTAWIFYGGAMLALIVMRYTKPNYPR-----PYKVP---- 464
            ||  :.:|::.......:.|:.....::...:||..:..|..|.......|     .:|.|
Yeast   435 LI--AFVAASKKEGEVFNWLLALSGLSSLFTWGGICICHIRFRKALAAQGRGLDELSFKSPTGVW 497

  Fly   465 -----IIIPVVVLVISVYLVAAPIFETPRVE-YLYALLFIFAGLIFYV 506
                 :.:.:::.:...|:...|:.::|..| :..|.|.....::.|:
Yeast   498 GSYWGLFMVIIMFIAQFYVAVFPVGDSPSAEGFFEAYLSFPLVMVMYI 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sbm	NP_727785.1	2A0308	53..532	CDD:273332	112/527 (21%)
GAP1	NP_012965.3	2A0310	87..566	CDD:273334	103/481 (21%)