DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sbm and TAT1

DIOPT Version :9

Sequence 1:	NP_727785.1	Gene:	sbm / 32397	FlyBaseID:	FBgn0030574	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_009625.1	Gene:	TAT1 / 852361	SGDID:	S000000273	Length:	619	Species:	Saccharomyces cerevisiae

Alignment Length:	518	Identity:	102/518 - (19%)
Similarity:	200/518 - (38%)	Gaps:	109/518 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 ERNGSTQN----HVVHLERRLGLFSGVALIVGTMIGSGIFVSPSGLLVRTGSVGVS-FIIWLACG 127
            |:|..|::    |:|.:....|:.:|:.:..|.::|:   ..|:||::..|...:. :.|..|.|
Yeast    86 EKNNLTKSIKSRHLVMISLGTGIGTGLLVGNGQVLGT---AGPAGLVLGYGIASIMLYCIIQAAG 147

  Fly   128 VLSLLGALAYAELGTMNTSSGAEWAYFMDAYGPAPAFLFS------WVSTLVLKPSQMAIICLSF 186
            .|    .|.||.|      :|....|......|:..|..|      |::.|.|:....|:....:
Yeast   148 EL----GLCYAGL------TGNYTRYPSILVDPSLGFAVSVVYTIQWLTVLPLQLVTAAMTVKYW 202

  Fly   187 AQYAVEAFVTECDPPRGVVKMVALVAIVMILFVNCYSVNLGMAVQNVFTAAKLVAV-------VV 244
            .....:.||.              |..|.::.:|.:........:.:|.:.|::.|       ::
Yeast   203 TSVNADIFVA--------------VVFVFVIIINLFGSRGYAEAEFIFNSCKILMVIGFVILAII 253

  Fly   245 VICGGAWKLMQGNTQHL-SNAFNGPMP---NVGAIATAFYTGLWAYDGWNNLNYVTEEIKNPSKN 305
            :.||||     |:.::: :..::.|.|   ....:.|.|....::|.|...|.....|.:||:|:
Yeast   254 INCGGA-----GDRRYIGAEYWHNPGPFAHGFKGVCTVFCYAAFSYGGIEVLLLSAAEQENPTKS 313

  Fly   306 LPRSIIIGIPLVTLCYAL--INISYLAAMSPQEMIESEAVAVTFGNRILGALA--------WLMP 360
            :|.:....:..:.|.|.|  |.:.:|...:..|::.|...:.:..:..:.|:|        ..:.
Yeast   314 IPNACKKVVYRILLIYMLTTILVCFLVPYNSDELLGSSDSSGSHASPFVIAVASHGVKVVPHFIN 378

  Fly   361 LSVTISTFGSANGTLFAAGRLCFAASREGHLLDILSYVHVRRLTPAPGLIFHSLIASAMVLHGTI 425
            ..:.||....||.:|::..||..:.:.:|.|...|:||. |...|.. ..|.||:...:....|.
Yeast   379 AVILISVISVANSSLYSGPRLLLSLAEQGVLPKCLAYVD-RNGRPLL-CFFVSLVFGCIGFVATS 441

  Fly   426 DSLIDFFSFTAWIFYGGAMLALIVMRYTKPNYPR---------------PYK---------VPII 466
            |:....|:   |:....::..|.:......::.|               .||         :.::
Yeast   442 DAEEQVFT---WLLAISSLSQLFIWMSMSLSHIRFRDAMAKQGRSMNEVGYKAQTGYWGSWLAVL 503

  Fly   467 IPVVVLVISVYLVAAPIFETPRV-------EYLYALLFIFA---------GLIFYVPFVKLGM 513
            |.:..||...::..||:.|..::       .||...:.:||         ...|::|..|:.:
Yeast   504 IAIFFLVCQFWVAIAPVNEHGKLNVKVFFQNYLAMPIVLFAYFGHKIYFKSWSFWIPAEKIDL 566

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sbm	NP_727785.1	2A0308	53..532	CDD:273332	102/518 (20%)
TAT1	NP_009625.1	2A0310	91..567	CDD:273334	100/513 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2200
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.950