DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sbm and AGP1

DIOPT Version :9

Sequence 1:	NP_727785.1	Gene:	sbm / 32397	FlyBaseID:	FBgn0030574	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_009905.3	Gene:	AGP1 / 850333	SGDID:	S000000530	Length:	633	Species:	Saccharomyces cerevisiae

Alignment Length:	600	Identity:	124/600 - (20%)
Similarity:	219/600 - (36%)	Gaps:	191/600 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 KNNST-------DNNRGHNVPTKTTSNGTMCANGSLGTE-------------------GP----E 51
            ||:||       ||...:   .:|.||....:...||.|                   ||    |
Yeast    14 KNSSTEIHATGQDNEIEY---FETGSNDRPSSQPHLGYEQHNTSAVRRFFDSFKRADQGPQDEVE 75

  Fly    52 APETDS-----SGTGRMRKPLERNGSTQNHVVHLERRLGLFSG---------------VALIVGT 96
            |.:.:.     |.:.|..:.||:|.|:.|        :|..:|               :.:.:||
Yeast    76 ATQMNDLTSAISPSSRQAQELEKNESSDN--------IGANTGHKSDSLKKTIQPRHVLMIALGT 132

  Fly    97 MIGSGIFV---------SPSGLLVRTGSVG-VSFIIWLACGVLSLLGALAYAELGTMNTSSGAEW 151
            .||:|:.|         .|:|||:....:| :.:.|..|||.:    ||.|:.|      :|...
Yeast   133 GIGTGLLVGNGTALVHAGPAGLLIGYAIMGSILYCIIQACGEM----ALVYSNL------TGGYN 187

  Fly   152 AY--FM--DAYGPAPAFLFSWVSTLVLKPSQMAIIC---LSFAQYAVEAFVTECDPPRGVVKMVA 209
            ||  |:  |.:|    |..:||..|     |...:|   |..|...::.:.|..:|     .:..
Yeast   188 AYPSFLVDDGFG----FAVAWVYCL-----QWLCVCPLELVTASMTIKYWTTSVNP-----DVFV 238

  Fly   210 LVAIVMILFVNCYSVNLGMAVQNVFTAAKLVAV-------VVVICGGAWK--LMQGNTQHLSNAF 265
            ::..|:::.:|.:........:..|...|::.:       :::..|||..  .:.|...|...||
Yeast   239 IIFYVLVITINIFGARGYAEAEFFFNCCKILMMTGFFILGIIIDVGGAGNDGFIGGKYWHDPGAF 303

  Fly   266 NG--PMPNVGAIATAFYTGLWAYDGWNNLNYVTEEIKNPSKNLP---RSIIIGIPLVTLCYALIN 325
            ||  .:.....:|....|..:|:.|...:...|.|..||.|.:|   :.:|..|..:.|. .:|.
Yeast   304 NGKHAIDRFKGVAATLVTAAFAFGGSEFIAITTAEQSNPRKAIPGAAKQMIYRILFLFLA-TIIL 367

  Fly   326 ISYLAAMSPQEMIESE---------AVAV-TFGNRILGALAWLMPLSVTISTFGSANGTLFAAGR 380
            :.:|...:..:::.|.         .:|| :.|.|:   :...:...:.:|....||.:.:::.|
Yeast   368 LGFLVPYNSDQLLGSTGGGTKASPYVIAVASHGVRV---VPHFINAVILLSVLSMANSSFYSSAR 429

  Fly   381 LCFAASREGHLLDILSYVH----------VRRL---------TPAPGLIFHSLIASAMVLHGTID 426
            |....|.:|:...:.||:.          |..|         :|....:|..|:|        |.
Yeast   430 LFLTLSEQGYAPKVFSYIDRAGRPLIAMGVSALFAVIAFCAASPKEEQVFTWLLA--------IS 486

  Fly   427 SLIDFFSFTAWIFYGGAMLALIVMRYTKPNYPRPYKV---------------------PIIIPVV 470
            .|...|::||        :.|..:|:.     |..||                     ..|:.::
Yeast   487 GLSQLFTWTA--------ICLSHLRFR-----RAMKVQGRSLGELGFKSQTGVWGSAYACIMMIL 538

  Fly   471 VLVISVYLVAAPIFE 485
            :|:...::..|||.|
Yeast   539 ILIAQFWVAIAPIGE 553

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sbm	NP_727785.1	2A0308	53..532	CDD:273332	107/533 (20%)
AGP1	NP_009905.3	2A0310	117..597	CDD:273334	98/485 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345715
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.850