Protein Alignment sbm and SLC7A3

DIOPT Version :9

• Sequence 1: NP_727785.1
• Gene: sbm / 32397
• FlyBaseID: FBgn0030574
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001041629.1
• Gene: SLC7A3 / 84889
• HGNCID: 11061
• Length: 619
• Species: Homo sapiens
• Alignment Length: 432
• Identity: 99/432 - (22%)
• Similarity: 183/432 - (42%)
• Gaps: 60/432 - (13%)

  Fly    64 RKPLERNGSTQNHVVHLERRLGLFSGVALIVGTMIGSGIFVSPSGLLVRTGSVGVSFII-WLACG 127
            |:.|| :|..:   ..|.|.|.....|||.||:.:|:|::|....  |.....|.|.:| :|...
Human    16 RRTLE-SGMAE---TRLARCLSTLDLVALGVGSTLGAGVYVLAGE--VAKDKAGPSIVICFLVAA 74

  Fly   128 VLSLLGALAYAELGTMNTSSGAEWAYFMDAYGPAPAFLFSW--VSTLVLKPSQMAIICLSFAQYA 190
            :.|:|..|.|||.|.....||:.:.|.....|...||...|  :.:.|:..:.:|....|.....
Human    75 LSSVLAGLCYAEFGARVPRSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNL 139

  Fly   191 VEAFVTE-------CDPPRGVVKMVALVAIVMILFVN---CYSVNLGMAVQNVFTAAKLVAVVVV 245
            :...:::       ...|..:.:.....|:.::|.:.   ....:....|..|||...|:.:..|
Human   140 IGNHISKTLQGSIALHVPHVLAEYPDFFALGLVLLLTGLLALGASESALVTKVFTGVNLLVLGFV 204

  Fly   246 ICGG-------AWKLMQGNTQ----HLSNAFN-GPMPNVGAI-----------ATAFYTGLWAYD 287
            :..|       .|||.:.:.:    .|::.:: ||:.:.|.:           ||.||    |:.
Human   205 MISGFVKGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVPFGFEGILRGAATCFY----AFV 265

  Fly   288 GWNNLNYVTEEIKNPSKNLPRSIIIGIPLVTLCYALINISYLAAMSPQEMIESEA----VAVTFG 348
            |::.:....||.:||.:::|..|:|.:.:..|.|..:: |.|..|.|...::.|:    ..:..|
Human   266 GFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVS-SALTLMMPYYQLQPESPLPEAFLYIG 329

  Fly   349 ---NRILGALAWLMPLSVTISTFGSANGTLFAAGRLCFAASREGHLLDILSYVHVRRLTPAPGLI 410
               .|.:.|:..|..||.::.      |::|...|:.:|.:.:|.|..:|:.:|....||....:
Human   330 WAPARYVVAVGSLCALSTSLL------GSMFPMPRVIYAMAEDGLLFRVLARIHTGTRTPIIATV 388

  Fly   411 FHSLIASAMVLHGTIDSLIDFFSFTAWIFYGGAMLALIVMRY 452
            ...:||:.|.....:..|:|..|....:.|....:.::::||
Human   389 VSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLILRY 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sbm	NP_727785.1	2A0308	53..532	CDD:273332	99/432 (23%)
SLC7A3	NP_001041629.1	2A0303	9..591	CDD:273330	99/432 (23%)
		AA_permease_C	539..589	CDD:290617

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920