DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sbm and Slc7a7

DIOPT Version :9

Sequence 1:	NP_727785.1	Gene:	sbm / 32397	FlyBaseID:	FBgn0030574	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_112631.1	Gene:	Slc7a7 / 83509	RGDID:	619902	Length:	512	Species:	Rattus norvegicus

Alignment Length:	487	Identity:	187/487 - (38%)
Similarity:	292/487 - (59%)	Gaps:	20/487 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 EAPETDSSGTGRMRKPLERNGSTQNHVVHLERRLGLFSGVALIVGTMIGSGIFVSPSGLLVRTGS 115
            ||.|.|.|..|....|....       |.|::.:.|.:||.||||.||||||||||.|:|:.:.|
  Rat    14 EADEADGSAQGDGAGPAAEQ-------VKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLMYSAS 71

  Fly   116 VGVSFIIWLACGVLSLLGALAYAELGTMNTSSGAEWAYFMDAYGPAPAFLFSWVSTLVLKPSQMA 180
            .|:|.:||...|:.|:.|||.||||||....|||.:||.::|:|...||:..|.|.|:::|:..|
  Rat    72 FGLSLVIWAVGGIFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQA 136

  Fly   181 IICLSFAQYAVEAFVTECDPPRGVVKMVALVAIVMILFVNCYSVNLGMAVQNVFTAAKLVAVVVV 245
            :|.::||.|.|:.....|..|....:::|...|.::.|:||..|..|..||::||.||::|::.|
  Rat   137 VIAITFANYMVQPLFPSCGAPYAAGRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAV 201

  Fly   246 ICGGAWKLMQGNTQHLSNAFNGPMPNVGAIATAFYTGLWAYDGWNNLNYVTEEIKNPSKNLPRSI 310
            |..|..:|.||.|.:..::|.|....:|.||.|.|:.|::|.||:.||||||||:||.:|||.||
  Rat   202 IIAGIVRLGQGATTNFEDSFEGSSFAMGDIALALYSALFSYSGWDTLNYVTEEIRNPERNLPLSI 266

  Fly   311 IIGIPLVTLCYALINISYLAAMSPQEMIESEAVAVTFGNRILGALAWLMPLSVTISTFGSANGTL 375
            .|.:|:||:.|.|.|::|.:.:..::::.|:||||||.::|.|...|.:||:|.:|.||..|.::
  Rat   267 GISMPIVTIIYLLTNVAYYSVLDIKDILASDAVAVTFADQIFGIFNWTIPLAVALSCFGGLNASI 331

  Fly   376 FAAGRLCFAASREGHLLDILSYVHVRRLTPAPGLIFHSLIASAMVLHGTIDSLIDFFSFTAWIFY 440
            .||.||.|..||||||.|.:..:||.|.||.|.|:|:.::|...:....|..||:::||:.|.|.
  Rat   332 VAASRLLFVGSREGHLPDAICMIHVERFTPVPSLLFNGILALVYLCVEDIFQLINYYSFSYWFFV 396

  Fly   441 GGAMLALIVMRYTKPNYPRPYKVPIIIPVVVLVISVYLVAAPIFETPRVEYLYALLFIFAGLIFY 505
            |.:::..:.:|:.:|:.|||.|:.:..|:|..:.:::|||.|:: :..:..|..:....:||.||
  Rat   397 GLSIVGQLYLRWKEPDRPRPLKLSLFFPIVFCLCTIFLVAVPLY-SDTINSLIGIGIALSGLPFY 460

  Fly   506 VPFVKLGMTP---------RFMNKVTLFFQLL 528
            ...:::   |         |.:...|.:.|::
  Rat   461 FLIIRV---PEHKRPLCLRRIVASTTRYLQII 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sbm	NP_727785.1	2A0308	53..532	CDD:273332	185/485 (38%)
Slc7a7	NP_112631.1	2A0308	24..496	CDD:273332	182/477 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100314
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.820