DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sbm and LOC688389

DIOPT Version :9

Sequence 1:	NP_727785.1	Gene:	sbm / 32397	FlyBaseID:	FBgn0030574	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	XP_001066729.3	Gene:	LOC688389 / 688389	RGDID:	1589989	Length:	469	Species:	Rattus norvegicus

Alignment Length:	473	Identity:	136/473 - (28%)
Similarity:	244/473 - (51%)	Gaps:	30/473 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 VHLERRLGLFSGVALIVGTMIGSGIFVSPSGLLVRTG-SVGVSFIIWLACGVLSLLGALAYAELG 141
            :.|.|.:|.|....:::||:||:||||||.|:|..:. ::.||..||..||:|.:|.||:..||.
  Rat     1 MRLSRTVGFFHVTMVLLGTIIGTGIFVSPKGVLKYSSLNIPVSLGIWAGCGLLVMLNALSLVELA 65

  Fly   142 TMNTSSGAEWAYFMDAYGPAPAFLFSWVSTLVLKPSQMAIICLS-------FAQYAVEAFVTECD 199
            |....|||.:.:...:.|...|||..|:        |:...||.       .|.|.::.|.|.|.
  Rat    66 TTFPVSGASYYFLKRSLGSLAAFLSLWI--------QLFSYCLGLGAHTLLIATYLIQPFYTGCP 122

  Fly   200 PPRGVVKMVALVAIVMILFVNCYSVNLGMAVQNVFTAAKLVAVVVVICGGAWKLMQGNTQHLS-- 262
            .|...:|.:::..:.....:|...|.....:|.:.:..|:..:..:...|...|:.|..:::|
  Rat   123 APELPIKCLSVAILWSFGILNAGGVKTVAWLQTISSMIKMSILCFISLTGLVLLVIGKKENVSKF 187

  Fly   263 -NAFNGPMPNVGAIATAFYTGLWAYDGWNNLNYVTEEIKNPSKNLPRSIIIGIPLVTLCYALINI 326
             ||.:..:||......|...|.:||.|...:..:..|||||||.:|:::|..:.:..:.|.|.|:
  Rat   188 ENALDAELPNASQTVEAILQGCFAYRGIFIVINIAGEIKNPSKIIPKAVISCLSITIMSYLLANV 252

  Fly   327 SYLAAMSPQEMIESEAVAVTFGNRILGALAWLMPLSVTISTFGSANGTLFAAGRLCFAASREGHL 391
            :||..::|:|:..|::|.:|:.||...::.|:|.|.:::|:..:....:.:|.|:|::||.||.:
  Rat   253 AYLTVLTPKEITTSDSVVITWVNRAYPSMQWVMSLGISLSSLTTTACGILSAARICYSASLEGQM 317

  Fly   392 LDILSYVHVRRLTPAPGLIFHSLIASAMVLHGTIDSLIDFFSFTAW---IFYGGAMLALIVMRYT 453
            ..|.|.:: ...:|...:....::::..::...:..||.:....:.   :.|   |:|::.:||.
  Rat   318 PFIFSMLN-NHQSPVVAVTQVVILSTVSIICSNLTYLIKYLGIMSIFNDVLY---MIAILKLRYQ 378

  Fly   454 KPNYPRPYKVPIIIPVVV--LVISVYLVAAPIFETPRVEYLYALLFIFAGLIFYVPFVKLGMTPR 516
            ||..||||||  .:|:|.  |.:|.:.:.|||.::|.:|::|..||:.:|.:.|...|.|.....
  Rat   379 KPALPRPYKV--CLPLVFGSLALSSFFILAPIIQSPNIEHIYEGLFLLSGFVVYWLQVYLYQHAD 441

  Fly   517 FMNKVTLFFQLLLEVVPT 534
            ....:|.:.|||..|:|:
  Rat   442 HFKTITCYLQLLFNVLPS 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sbm	NP_727785.1	2A0308	53..532	CDD:273332	134/469 (29%)
LOC688389	XP_001066729.3	PotE	1..437	CDD:223605	129/449 (29%)
LOC688389	XP_001066729.3	SLC5-6-like_sbd	5..>266	CDD:294310	79/268 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351233
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D385385at33208
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11785
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.850