Protein Alignment sbm and SLC7A2

DIOPT Version :9

• Sequence 1: NP_727785.1
• Gene: sbm / 32397
• FlyBaseID: FBgn0030574
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_001158243.1
• Gene: SLC7A2 / 6542
• HGNCID: 11060
• Length: 698
• Species: Homo sapiens
• Alignment Length: 635
• Identity: 128/635 - (20%)
• Similarity: 237/635 - (37%)
• Gaps: 152/635 - (23%)

  Fly    29 VPTKTTSNGTMCANGSLGTEGPEAPETDS------SGTGRM--------------RKPLERNGST 73
            :.|...::..:...|.:||..|  |..||      |...||              |:.:....|.
Human     3 IETSGYNSDKLICRGFIGTPAP--PVCDSKFLLSPSSDVRMIPCRAALTFARCLIRRKIVTLDSL 65

  Fly    74 QNHVVHLERRLGLFSGVALIVGTMIGSGIFVSPSGLLVRTGSVGVSFII-WLACGVLSLLGALAY 137
            ::  ..|.|.|.....:||.||:.:|:|::|. :|.:.:..| |.|.:: :|...:.|::..|.|
Human    66 ED--TKLCRCLSTMDLIALGVGSTLGAGVYVL-AGEVAKADS-GPSIVVSFLIAALASVMAGLCY 126

  Fly   138 AELGTMNTSSGAEWAYFMDAYGPAPAFLFSW--VSTLVLKPSQMA---------IICLSFAQYAV 191
            ||.|.....:|:.:.|.....|...||:..|  :.:.|:..|.:|         ::.....|:..
Human   127 AEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLSKQIGQFLR 191

  Fly   192 EAFVTECDPPRGVVKMVALVAIVMILFVN---CYSVNLGMAVQNVFTAAKLVAVVVVICGG---- 249
            ..|....   .|:.:.....|:.:||.:.   .:.|.....|..||||..::.::.|:..|
Human   192 TYFRMNY---TGLAEYPDFFAVCLILLLAGLLSFGVKESAWVNKVFTAVNILVLLFVMVAGFVKG 253

  Fly   250 ---AWKLMQGNTQHLSNAFNGP--------------MP-----NVGAIATAFYTGLWAYDGWNNL 292
               .||:.:...:::|.:...|              ||     .:...||.||    |:.|::.:
Human   254 NVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFTGTLAGAATCFY----AFVGFDCI 314

  Fly   293 NYVTEEIKNPSKNLPRSIIIGIPLVTLCYALINISYLAAMSPQEMI-ESEAVAVTFGNRILGALA 356
            ....||::||.|.:|..|:..:.:..:.|..::.: |..|.|..:: |...:.|.|.....|...
Human   315 ATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAA-LTLMMPYYLLDEKSPLPVAFEYVGWGPAK 378

  Fly   357 WLMPLSVTISTFGSANGTLFAAGRLCFAASREGHLLDILSYVHVRRLTPAPGLIFHSLIASAMVL 421
            :::......:...|..|::|...|:.:|.:.:|.|...|:.::.:..||....:....:|:.|..
Human   379 YVVAAGSLCALSTSLLGSIFPMPRVIYAMAEDGLLFKCLAQINSKTKTPIIATLSSGAVAALMAF 443

  Fly   422 HGTIDSLIDFFSFTAWIFYGGAMLALIVMRYTKP--NYPRP------------------------ 460
            ...:.:|:|..|....:.|......::::|| :|  :|.:|
Human   444 LFDLKALVDMMSIGTLMAYSLVAACVLILRY-QPGLSYDQPKCSPEKDGLGSSPRVTSKSESQVT 507

  Fly   461 -----------YKVPIIIPV----------------VVLVISVYLVAAPIFETPRVE-YLYALLF 497
                       ...|.::|.                :||.:|| |....:....|:| :..|||.
Human   508 MLQRQGFSMRTLFCPSLLPTQQSASLVSFLVGFLAFLVLGLSV-LTTYGVHAITRLEAWSLALLA 571

  Fly   498 IFAGLI------------------FYVPFVKLGMTPRFMNKVTLFFQLLL 529
            :|..|.                  |.|||  |...|.|...|.::..:.|
Human   572 LFLVLFVAIVLTIWRQPQNQQKVAFMVPF--LPFLPAFSILVNIYLMVQL 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sbm	NP_727785.1	2A0308	53..532	CDD:273332	123/611 (20%)
SLC7A2	NP_001158243.1	2A0303	45..648	CDD:273330	117/591 (20%)
		AA_permease_C	596..646	CDD:290617	9/26 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157248
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.850