DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sbm and slc7a10b

DIOPT Version :9

Sequence 1:	NP_727785.1	Gene:	sbm / 32397	FlyBaseID:	FBgn0030574	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	XP_687825.2	Gene:	slc7a10b / 559395	ZFINID:	ZDB-GENE-121105-2	Length:	517	Species:	Danio rerio

Alignment Length:	502	Identity:	186/502 - (37%)
Similarity:	294/502 - (58%)	Gaps:	22/502 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 EGPEAPETDSSGTGRMRKPLERNGSTQNHVVHLERRLGLFSGVALIVGTMIGSGIFVSPSGLLVR 112
            :|.|..:|::..:......|:|:......|. |::.:||.|...:|:|.:||||||:||.|:|..
Zfish     2 DGVERKKTEARRSIMKDSELKRDSGIPERVT-LKKEIGLLSACTIIIGNIIGSGIFISPKGVLEH 65

  Fly   113 TGSVGVSFIIWLACGVLSLLGALAYAELGTMNTSSGAEWAYFMDAYGPAPAFLFSWVSTLVLKPS 177
            :||||::.::|:..|.::.||:|.|||||.....||.:::|..:.:|....||..|.:.|::.|:
Zfish    66 SGSVGLALVVWMLGGGVAALGSLCYAELGVTIPKSGGDYSYVTEIFGGLVGFLLLWSAVLIMYPT 130

  Fly   178 QMAIICLSFAQYAVEAFVTECDPPRGVVKMVALVAIVMILFVNCYSVNLGMAVQNVFTAAKLVAV 242
            .:|:|.|:|:.|.::.....|.||....:|::.:.|:.:.:||||||.|...:|:.||..||:|:
Zfish   131 TLAVIALTFSSYVLQPVFPHCVPPYIATRMLSAICILFLTWVNCYSVRLATRIQDAFTVGKLLAL 195

  Fly   243 VVVICGGAWKLMQGNTQHLS--NAFN-GPMPNVGAIATAFYTGLWAYDGWNNLNYVTEEIKNPSK 304
            .::|..|..::..||.:.|:  .||. ...|::|.||.||....:|:.|||.|||||||:.:|.:
Zfish   196 GLIITVGLVQICGGNYESLTPQTAFTFNKAPSIGQIALAFLHASFAFSGWNFLNYVTEEVVDPRR 260

  Fly   305 NLPRSIIIGIPLVTLCYALINISYLAAMSPQEMIESEAVAVTFGNRILGALAWLMPLSVTISTFG 369
            ||||:|.|.|||||..|.|.||:|.::|||:|::.|.|||||||.::||..:.|||:||.:||||
Zfish   261 NLPRAIYISIPLVTCVYTLTNIAYFSSMSPEELLSSNAVAVTFGEKLLGMFSTLMPISVALSTFG 325

  Fly   370 SANGTLFAAGRLCFAASREGHLLDILSYVHVRRLTPAPGLIFHSLIASAMVLHGTIDSLIDFFSF 434
            ..||.||.:.||||:.:|||||..:|:.:|.:..||.|.|:........::..|...:||::.||
Zfish   326 GINGYLFTSSRLCFSGAREGHLPSLLAMIHFKHCTPIPALLVCCTATIVILCIGETHNLINYVSF 390

  Fly   435 TAWIFYGGAMLALIVMRYTKPNYPRPYKVPIIIPVVVLVISVYLVAAPIFETPRVEYLYALLFIF 499
            ..::.||..:..|:..|:.|||..||.||.:::||..|:....|:|..:...|.|..: .|:.:.
Zfish   391 INYLSYGVTIAGLLYYRWKKPNLYRPIKVSLLVPVCYLLFWALLLAFSLHSEPLVCGV-GLVIML 454

  Fly   500 AGLIFYVPFVKLGM----TPRFMNKVT---------LFFQLLLEVVP 533
            .|    ||...||:    .||.:...|         :||.:..::.|
Zfish   455 TG----VPVYFLGVYWKDKPRCIYDFTEWATYLGQRVFFVVFPQIDP 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sbm	NP_727785.1	2A0308	53..532	CDD:273332	183/494 (37%)
slc7a10b	XP_687825.2	2A0308	29..494	CDD:273332	180/470 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100314
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.720