DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sbm and slc7a14b

DIOPT Version :9

Sequence 1:	NP_727785.1	Gene:	sbm / 32397	FlyBaseID:	FBgn0030574	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	XP_684639.2	Gene:	slc7a14b / 556696	ZFINID:	ZDB-GENE-091113-47	Length:	756	Species:	Danio rerio

Alignment Length:	444	Identity:	113/444 - (25%)
Similarity:	193/444 - (43%)	Gaps:	65/444 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 PEAPETDSSGTG-----RMRKPLER--NGSTQNHVVHLERRLGLFSGVALIVGTMIGSGIFVSPS 107
            |...|.|||..|     ...||::.  .||...|...|...|.....|:|.||:.:|:|::| .:
Zfish    10 PRRIEWDSSWYGLHSRILRTKPVDSMLEGSGDLHGTRLASVLTTVDLVSLGVGSCVGTGMYV-VA 73

  Fly   108 GLLVRT---GSVGVSFIIWLACGVLSLLGALAYAELGT-MNTSSGAEWAYFMDAYGPAPAFLFSW 168
            ||:.:.   ..|.:||||   ..|.|:|..:.|||.|. :..::|:.:.|.....|...||...|
Zfish    74 GLVAKEMAGPGVILSFII---AAVASILSGVCYAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGW 135

  Fly   169 VSTLVLK--------PSQMAIICLSFAQYAVEAF-VTECDPPRGVVK-------MVALVAIVMIL 217
              .|:|:        .|.::.:..|.|.:.:..: :.......|:.|       ::||:..:::.
Zfish   136 --NLILEYLIGTAAGASALSSMFDSLANHTISRYMINHLGTLNGLGKGEESYPDLLALLIALVVT 198

  Fly   218 FVNCYSVNLGMAVQNVFTAAKLVAVVVVICGGAWKLMQGNTQ---HLSNAFNGPMPNVGAIATAF 279
            .:....|...::..||.....||..|.::..|.:.|...|.:   .|...::|.|.  || ||.|
Zfish   199 VIIALGVKNSVSFNNVLNVVNLVVWVFMVLAGLFFLSGANWEGGRFLPYGWSGVMQ--GA-ATCF 260

  Fly   280 YTGLWAYDGWNNLNYVTEEIKNPSKNLPRSIIIGIPLVTLCYALINIS-YLAAMSPQEMIESEAV 343
            |    |:.|::.:....||.|:|..::|.:|...  |||...|.:::| .|..:.|..:|:.:|.
Zfish   261 Y----AFIGFDIIATTGEEAKSPDTSIPYAITAS--LVTCLTAYVSVSVILTLLVPYNLIDGDAP 319

  Fly   344 AVTF--------GNRI--LGALAWLMPLSVTISTFGSANGTLFAAGRLCFAASREGHLLDILSYV 398
            .:..        |..|  :||:|.|     |:|..||    ||...|:.:|.:.:|.|...||:|
Zfish   320 LMEMFADHGFLAGKYIVAVGAVAGL-----TVSLLGS----LFPMPRVIYAMAGDGLLFRFLSFV 375

  Fly   399 HVRRLTPAPGLIFHSLIASAMVLHGTIDSLIDFFSFTAWIFYGGAMLALIVMRY 452
            .....||.........:|:.:.|..::..||:..|....:.|....:.::::||
Zfish   376 SPHTETPVVACAVSGSLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRY 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sbm	NP_727785.1	2A0308	53..532	CDD:273332	112/441 (25%)
slc7a14b	XP_684639.2	2A0303	26..666	CDD:273330	107/428 (25%)
slc7a14b	XP_684639.2	AA_permease_C	616..666	CDD:290617
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010