DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sbm and Slc7a5

DIOPT Version :9

Sequence 1:	NP_727785.1	Gene:	sbm / 32397	FlyBaseID:	FBgn0030574	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_059049.1	Gene:	Slc7a5 / 50719	RGDID:	620639	Length:	512	Species:	Rattus norvegicus

Alignment Length:	498	Identity:	206/498 - (41%)
Similarity:	303/498 - (60%)	Gaps:	17/498 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 APETDSSGTGRM--RKPLE-RNG---STQNHVVHLERRLGLFSGVALIVGTMIGSGIFVSPSGLL 110
            ||.|.::...|.  .|.|| |.|   ..:...|.|:|.:.|.:|||:||||:|||||||:|:|:|
  Rat    13 APATTAAEEERQAREKMLEARRGDGADPEGEGVTLQRNITLINGVAIIVGTIIGSGIFVTPTGVL 77

  Fly   111 VRTGSVGVSFIIWLACGVLSLLGALAYAELGTMNTSSGAEWAYFMDAYGPAPAFLFSWVSTLVLK 175
            ...||.|:|.::|..|||.|::|||.||||||..:.||.::||.::.||..||||..|:..|:::
  Rat    78 KEAGSPGLSLVVWAVCGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIR 142

  Fly   176 PSQMAIICLSFAQYAVEAFVTECDPPRGVVKMVALVAIVMILFVNCYSVNLGMAVQNVFTAAKLV 240
            ||...|:.|.||.|.::.....|..|....|:||.:.::::..||||||.....||:.|.||||:
  Rat   143 PSSQYIVALVFATYLLKPVFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLL 207

  Fly   241 AVVVVICGG----AWKLMQGNTQHLSN--AFNGPMPNVGAIATAFYTGLWAYDGWNNLNYVTEEI 299
            |:.::|..|    ...:.||:..:|..  :|.|...:||.|..|.|:||:||.|||.||:||||:
  Rat   208 ALALIILLGFIQMGKDIGQGDASNLHQKLSFEGTNLDVGNIVLALYSGLFAYGGWNYLNFVTEEM 272

  Fly   300 KNPSKNLPRSIIIGIPLVTLCYALINISYLAAMSPQEMIESEAVAVTFGNRILGALAWLMPLSVT 364
            .||.:|||.:|||.:|:|||.|.|.|::|...:|..:|:.||||||.|||..||.::|::|:.|.
  Rat   273 INPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTNQMLTSEAVAVDFGNYHLGVMSWIIPVFVG 337

  Fly   365 ISTFGSANGTLFAAGRLCFAASREGHLLDILSYVHVRRLTPAPGLIFHSLIASAMVLHGTIDSLI 429
            :|.|||.||:||.:.||.|..||||||..|||.:|.:.|||.|.|:|..::.........|.|:|
  Rat   338 LSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLMYAFSRDIFSII 402

  Fly   430 DFFSFTAWIFYGGAMLALIVMRYTKPNYPRPYKVPIIIPVVVLVISVYLVAAPIFETPRVEYLYA 494
            :||||..|:....|::.::.:|:.||...||.||.:.:||..::..::|:|...::|| :|....
  Rat   403 NFFSFFNWLCVALAIIGMMWLRFKKPELERPIKVNLALPVFFILACLFLIAVSFWKTP-LECGIG 466

  Fly   495 LLFIFAGLIFYVPFVKLGMTPRFMNK----VTLFFQLLLEVVP 533
            ...|.:||..|...|.....|:::.:    ||:..|.|::|||
  Rat   467 FAIILSGLPVYFFGVWWKNKPKWILQVIFSVTVLCQKLMQVVP 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sbm	NP_727785.1	2A0308	53..532	CDD:273332	202/494 (41%)
Slc7a5	NP_059049.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..43		9/29 (31%)
Slc7a5	NP_059049.1	2A0308	23..511	CDD:273332	203/488 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D621852at2759
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100314
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.730