DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sbm and JhI-21

DIOPT Version :9

Sequence 1:	NP_727785.1	Gene:	sbm / 32397	FlyBaseID:	FBgn0030574	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_001245996.1	Gene:	JhI-21 / 34624	FlyBaseID:	FBgn0028425	Length:	500	Species:	Drosophila melanogaster

Alignment Length:	489	Identity:	200/489 - (40%)
Similarity:	303/489 - (61%)	Gaps:	24/489 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 ANG---SL--GTEGPEAPETDSSGTGRMRKPLERNGSTQNHVVHLERRLGLFSGVALIVGTMIGS 100
            |||   ||  .|.|..||...:...|..:             :.|:|:|.|.:|||:||||:|||
  Fly     6 ANGVTTSLVEPTNGCAAPGNPNPADGEEK-------------IVLKRKLTLINGVAIIVGTIIGS 57

  Fly   101 GIFVSPSGLLVRTGSVGVSFIIWLACGVLSLLGALAYAELGTMNTSSGAEWAYFMDAYGPAPAFL 165
            |||::|:|:.:.|.|||.|.:|||.||:||.:|||.||||||..|.||.::||.:.::||...||
  Fly    58 GIFIAPTGVFIYTESVGSSLLIWLTCGILSTIGALCYAELGTCITRSGGDYAYLLVSFGPLVGFL 122

  Fly   166 FSWVSTLVLKPSQMAIICLSFAQYAVEAFVTECDPPRGVVKMVALVAIVMILFVNCYSVNLGMAV 230
            ..|::.|:::|:...|:.||||.|||:.|..|||||:..||::|.:.:.::..:||.||.:.|.|
  Fly   123 RLWIALLIIRPTTQTIVALSFAHYAVKPFFPECDPPQNAVKLLAAICLTLLTTINCLSVKVSMKV 187

  Fly   231 QNVFTAAKLVAVVVVICGGAWKLMQGNTQHLSNAFNG--PMPNVGAIATAFYTGLWAYDGWNNLN 293
            |:|||..||:|::::|..|.:.:..|..::..|.:.|  ...|:|   .|||:||:|:.|||.||
  Fly   188 QDVFTVGKLLALIMIILSGLYYMATGELENFRNPWEGIYTARNIG---YAFYSGLFAFGGWNYLN 249

  Fly   294 YVTEEIKNPSKNLPRSIIIGIPLVTLCYALINISYLAAMSPQEMIESEAVAVTFGNRILGALAWL 358
            :||||:::|.|||||:|.|.:||||..|.|:|::|.|.::..||:.|.|||||||||:.|.||::
  Fly   250 FVTEELQDPYKNLPRAIWIAMPLVTSIYVLVNLAYFAVVNKPEMLSSLAVAVTFGNRVFGPLAFM 314

  Fly   359 MPLSVTISTFGSANGTLFAAGRLCFAASREGHLLDILSYVHVRRLTPAPGLIFHSLIASAMVLHG 423
            :|:.|.:||||..||.||.:.||....::||||.......||::.||.|.|||..|::..|:|..
  Fly   315 VPIFVALSTFGGVNGVLFTSARLFATGAQEGHLPKFFQLFHVKQQTPIPSLIFTCLMSLLMLLTD 379

  Fly   424 TIDSLIDFFSFTAWIFYGGAMLALIVMRYTKPNYPRPYKVPIIIPVVVLVISVYLVAAPIFETPR 488
            .:..||::||...|:....::..::.:|:.:|:.|||.||.:.:|:..:|..|.||..|..|.|:
  Fly   380 NVYQLINYFSSVLWLSVVASIAGMLWLRHKRPDLPRPIKVHLALPITFMVSCVTLVLLPNLEEPQ 444

  Fly   489 VEYLYALLFIFAGLIFYVPFVKLGMTPRFMNKVT 522
             ..|..:....||:.||..|:.....|:...:::
  Fly   445 -NLLIGIGITLAGIPFYYAFIARKKKPKCYGRLS 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sbm	NP_727785.1	2A0308	53..532	CDD:273332	192/472 (41%)
JhI-21	NP_001245996.1	AA_permease_2	27..494	CDD:330980	191/468 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	128	1.000	Domainoid score	I255
eggNOG	1	0.900	-	-		E2759_KOG1287
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	139	1.000	Inparanoid score	I235
Isobase	1	0.950	-	0	Normalized mean entropy	S1752
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D621852at2759
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	1	1.000	-	-		mtm9156
orthoMCL	1	0.900	-	-		OOG6_100314
Panther	1	1.100	-	-	P	PTHR11785
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2200
SonicParanoid	1	1.000	-	-		X75
	12	11.850