DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sbm and Slc7a9

DIOPT Version :9

Sequence 1:	NP_727785.1	Gene:	sbm / 32397	FlyBaseID:	FBgn0030574	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_001185944.1	Gene:	Slc7a9 / 30962	MGIID:	1353656	Length:	487	Species:	Mus musculus

Alignment Length:	474	Identity:	257/474 - (54%)
Similarity:	343/474 - (72%)	Gaps:	2/474 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 RMRKPLERNGSTQNHVVHLERRLGLFSGVALIVGTMIGSGIFVSPSGLLVRTGSVGVSFIIWLAC 126
            |.|:..:...||:.....|::.:||.||:.:||||:||||||:||..:|..|.|||...|||.||
Mouse     8 RRREDEKSTHSTELKTTSLQKEVGLLSGICIIVGTIIGSGIFISPKSVLANTESVGPCLIIWAAC 72

  Fly   127 GVLSLLGALAYAELGTMNTSSGAEWAYFMDAYGPAPAFLFSWVSTLVLKPSQMAIICLSFAQYAV 191
            |:|:.||||.:||||||.|.||.|:.|.|:|:||.||:||||.|.:|:|||..|||||||::|..
Mouse    73 GILATLGALCFAELGTMITKSGGEYPYLMEAFGPIPAYLFSWTSLIVMKPSSFAIICLSFSEYVC 137

  Fly   192 EAFVTECDPPRGVVKMVALVAIVMILFVNCYSVNLGMAVQNVFTAAKLVAVVVVICGGAWKLMQG 256
            .||.:.|.||..|||::|..||:.|..||..||.||..|||||||||:|.|.::|..|...|.||
Mouse   138 AAFYSGCKPPAVVVKLLAAAAILFITTVNALSVRLGSYVQNVFTAAKMVIVAIIIISGLVFLAQG 202

  Fly   257 NTQHLSNAFNGPMPNVGAIATAFYTGLWAYDGWNNLNYVTEEIKNPSKNLPRSIIIGIPLVTLCY 321
            |.::..|:|.|...:||||:.|||.|||||||||.|||:|||::||.:|||.:|:|||||||:||
Mouse   203 NVKNFQNSFEGTQTSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPMAIVIGIPLVTVCY 267

  Fly   322 ALINISYLAAMSPQEMIESEAVAVTFGNRILGALAWLMPLSVTISTFGSANGTLFAAGRLCFAAS 386
            .|:||:|...|:|.|:::|:|||||||:|:|...:|::||.|..||.|:||||.|.||||.:.|.
Mouse   268 ILMNIAYFTVMTPTELLQSQAVAVTFGDRVLYPASWVVPLFVAFSTIGAANGTCFTAGRLIYVAG 332

  Fly   387 REGHLLDILSYVHVRRLTPAPGLIFHSLIASAMVLHGTIDSLIDFFSFTAWIFYGGAMLALIVMR 451
            ||||:|.:|||:.|:||||||.|||:.:||...::.|.|:||:::|||.||:|||..:|.|:|||
Mouse   333 REGHMLKVLSYISVKRLTPAPALIFYGIIAIIYIIPGDINSLVNYFSFAAWLFYGMTILGLVVMR 397

  Fly   452 YTKPNYPRPYKVPIIIPVVVLVISVYLVAAPIFETPRVEYLYALLFIFAGLIFYVPFV--KLGMT 514
            :|:.:..||.|||:.||::|:::|::|:.|||...|..||||.:|||.:|||||..||  |.|..
Mouse   398 FTRKDLERPIKVPLFIPIIVILVSLFLILAPIISEPAWEYLYCVLFILSGLIFYFLFVYYKFGWA 462

  Fly   515 PRFMNKVTLFFQLLLEVVP 533
            .|....||...|:|:||||
Mouse   463 QRISRPVTKHLQMLMEVVP 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sbm	NP_727785.1	2A0308	53..532	CDD:273332	254/471 (54%)
Slc7a9	NP_001185944.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20		3/11 (27%)
Slc7a9	NP_001185944.1	2A0308	26..484	CDD:273332	253/456 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	488	1.000	Domainoid score	I381
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56668
Inparanoid	1	1.050	539	1.000	Inparanoid score	I1169
Isobase	1	0.950	-	0	Normalized mean entropy	S1752
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D385385at33208
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	1	1.000	-	-		oto91893
orthoMCL	1	0.900	-	-		OOG6_100314
Panther	1	1.100	-	-	LDO	PTHR11785
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2200
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	15	14.860