DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sbm and SPAPB24D3.02c

DIOPT Version :9

Sequence 1:	NP_727785.1	Gene:	sbm / 32397	FlyBaseID:	FBgn0030574	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_593989.1	Gene:	SPAPB24D3.02c / 2543419	PomBaseID:	SPAPB24D3.02c	Length:	543	Species:	Schizosaccharomyces pombe

Alignment Length:	538	Identity:	117/538 - (21%)
Similarity:	198/538 - (36%)	Gaps:	109/538 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 GPEAPETDSSGTGRMRKPLERNGSTQNHVVHLERRLGLFSGVALIVGTMIGS-GIFVSPSGLLVR 112
            |..||.|:..      |.|...|..|    ..:|...|.:    :.|...|| |:..|..|.:..
pombe    22 GESAPVTEDD------KMLLNLGYKQ----EFKREFSLLA----VFGQSFGSMGLCPSLVGSMAF 72

  Fly   113 TGSVGVSFIIW-LACGVLSLLG-ALAYAELGTMNTSSGAEWAYFMDAYGPAP---AFLFSWVSTL 172
            :.:.|...::| ...|...||. |.|.:||.:...:||:  .||..||...|   ||| ||....
pombe    73 SMNCGAGGMVWSWFVGATCLLPIAFALSELASSMPTSGS--LYFWTAYLSPPKYRAFL-SWFLGY 134

  Fly   173 VLKPSQMAIICLSFAQ--YA----VEAFVTECDPPRGVVK-------------MVALVAIVMILF 218
            ||..:...    .||.  ||    |:|..:..:|.....|             ..||:.:.....
pombe   135 VLALAYST----GFASTIYAAAGLVQATASVANPSYAPTKYEEYGIYVALSFACSALIVLPTKFL 195

  Fly   219 VNCYSVNLGMAVQNVFTAAKLVAVVVVICGGAWKLMQGNTQHLSNAFN--GPMPNVG-AIATAFY 280
            ....|.|:      ||....::..::.:...:....:....::...|.  ....|:| :....|.
pombe   196 ARFSSFNV------VFQICTILIFIISLAASSTSETRNTGSYIFGNFENYSGWTNMGWSFILCFT 254

  Fly   281 TGLWAYDGWNNLNYVTEEIKNPSKNLPRSIIIGIPLVTLCYALINISYLAAM---------SPQE 336
            |.:|...|:.:...:.||.||.||..|.:||..:.:.......|.|:....|         :|..
pombe   255 TPVWVLSGFESCATIVEEAKNASKAAPIAIISSLTVSLFMGFCIMITIAGTMGHDFSSILNTPYG 319

  Fly   337 MIESEAVAVTFGNRILGALAWLMPLSVTISTFGSANGTLFAAGRLCFAASREGHLLDILSYVH-- 399
            ...|:.:....|.|  ||:.....|.:.:         .|....||.|:|||     |.::..
pombe   320 EPVSQVLYNNLGKR--GAVGVSAVLIIAL---------CFNCSALCLASSRE-----IFAFARDK 368

  Fly   400 -------VRRLTPAPGL---------IFHSLIASAMVLHGT-IDSLIDFFSFTAWIFYGGAMLAL 447
                   .|:|||. |:         ::..::...|:::.| |.|:.:......:|.|...::..
pombe   369 GLPGSWIFRKLTPG-GIPLNAILLVNLYTIIVGLLMLVNVTAISSIFNLAIIAFFISYSLPLVCR 432

  Fly   448 IVMRYTKPN--YPRPYKVPI-IIPVVVLVISVYLVAAPIFETP-RVEYLYALLFIFAGLIFYVPF 508
            ::.....|.  |...:..|| |:.|..|.....::..|.::.| :||..:|::.:...:.|.|.:
pombe   433 LLFNRLNPGKFYCGKFSKPISIVAVAWLWFMALMLLFPSYQNPNKVEMNWAIVVLGFTVFFCVGY 497

  Fly   509 VKLGMTPRFMNKVTLFFQ 526
            ..|   |::..|.  ||:
pombe   498 YYL---PKYGGKT--FFK 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sbm	NP_727785.1	2A0308	53..532	CDD:273332	115/534 (22%)
SPAPB24D3.02c	NP_593989.1	2A0304	34..512	CDD:273331	112/520 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	71	1.000	Inparanoid score	I1915
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050