DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sbm and SPCC584.13

DIOPT Version :9

Sequence 1:	NP_727785.1	Gene:	sbm / 32397	FlyBaseID:	FBgn0030574	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	NP_588218.1	Gene:	SPCC584.13 / 2539095	PomBaseID:	SPCC584.13	Length:	544	Species:	Schizosaccharomyces pombe

Alignment Length:	474	Identity:	106/474 - (22%)
Similarity:	184/474 - (38%)	Gaps:	113/474 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   107 SGLLVRTGSVGVSFII--WLACGVLSLLGALAYAEL-GTMNTSSGAEWAYFMDA---YGPAPAFL 165
            |.:...||..|...::  ||...|.....|...||| .:|.||.|..:|..:.|   :||..|:|
pombe    62 STMYYTTGYAGTPAMVWGWLIAMVFVQCVANGMAELCSSMPTSGGLYYAAAVLAPKGWGPFAAWL 126

  Fly   166 FSWVSTLVL---KPS---QMAIICLSFAQYAVEAFVTECDPPRGVVKMVALVAIVMILFVNCYSV 224
            ..|.:.||.   .||   ..|.:.|:..|.....|.|:    ...:.::|:.|::...|::....
pombe   127 TGWSNYLVQVTGPPSVAYSFAGMILTLVQLHNPNFETQ----NYQIFLLAVAAMIAQGFISSMPT 187

  Fly   225 NL-------GMAVQNVFTAAKLVAVVVVICGGAWKLMQG-NTQH-LSNAFNG--PMPNVGAIATA 278
            .:       |..:..:|.|..::.|:.|   ...|..:| |:.| :.|.|:.  ...|..|:..:
pombe   188 KVLAVFNTWGTVLNMLFLAIVMITVLAV---AGTKTPRGFNSNHKVWNEFDNQTDWSNGMAMLMS 249

  Fly   279 FYTGLWAYDGWNNLNYVTEEIKNPSKNLPRSIII-----GIP--LVTLCYALINISYLAAMSP-- 334
            |...:|...|:::..:::||..|.|...||:|::     ||.  |:.||.|...:...|||:.
pombe   250 FAGVIWTMSGYDSPFHLSEECSNASVAAPRAIVMTSAFGGIVGWLLNLCIAYTIVDVNAAMNDDL 314

  Fly   335 ---------QEMIESEAVAVTFGNRILGALAWLMPLSVT-ISTFGSANGTLFAAGRLCFAASREG 389
                     |.......||:|               |:| |.:|....|.:.||.|:.::.:|:|
pombe   315 GQPFVVYLRQVCNYKTTVALT---------------SLTVICSFMMGQGCMVAASRVTYSYARDG 364

  Fly   390 --HLLDILSYVHVRRLTP--------APGLIFHSLI-ASAMVLHG--TIDSLIDFFSFTAWIFY- 440
              .....|:.|..|..||        ..|::...|| |....::.  ::.::..|.:||..||.
pombe   365 VFPFSKYLAIVDKRTKTPNVCVWMNVVVGILCCLLIFAGEAAINAIFSVGAIAAFVAFTTPIFLR 429

  Fly   441 -----------------------GGAMLALIVMRYT---------KPNYPRPYKVPIII---PVV 470
                                   |.|..|.:::...         |.|.|.......::   |::
pombe   430 VFFVKEDEFKRGPWHLGKFSKINGYAACAFVLLMVPILCFPQFRGKDNTPDAMNWTCVVFGGPML 494

  Fly   471 VLVISVYLVAAPIFETPRV 489
            :::|..::.|...|:.||:
pombe   495 MVLIWWFVSARKWFKGPRL 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sbm	NP_727785.1	2A0308	53..532	CDD:273332	106/474 (22%)
SPCC584.13	NP_588218.1	2A0304	28..511	CDD:273331	104/470 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	71	1.000	Domainoid score	I2614
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	71	1.000	Inparanoid score	I1915
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.050