DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sbm and AgaP_AGAP001627

DIOPT Version :9

Sequence 1:	NP_727785.1	Gene:	sbm / 32397	FlyBaseID:	FBgn0030574	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	XP_321470.3	Gene:	AgaP_AGAP001627 / 1281545	VectorBaseID:	AGAP001627	Length:	497	Species:	Anopheles gambiae

Alignment Length:	457	Identity:	184/457 - (40%)
Similarity:	299/457 - (65%)	Gaps:	7/457 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 LERRLGLFSGVALIVGTMIGSGIFVSPSGLLVRTGSVGVSFIIWLACGVLSLLGALAYAELGTMN 144
            |:.::.|.:|:.:|||::|||||||||:|:|:.||||.:|.|:|:..|:.|::||..|||||||.
Mosquito    39 LKPKMTLVNGITVIVGSIIGSGIFVSPTGVLINTGSVNMSLIVWILSGLFSMVGAYCYAELGTMI 103

  Fly   145 TSSGAEWAYFMDAYGPAPAFLFSWVSTLVLKPSQMAIICLSFAQYAVEAFVTECDPPRGVVKMVA 209
            ..|||::||.|:.:||..||:..|:..::::|...||:.|:|:.|.::.|..||.||....:::|
Mosquito   104 KKSGADYAYIMETFGPFLAFIRLWIECMIVRPCSQAIVALTFSVYVLKPFFPECQPPEDAARLLA 168

  Fly   210 LVAIVMILFVNCYSVNLGMAVQNVFTAAKLVAVVVVICGGAWKLMQGNTQHLSNAFNGPMPNVGA 274
            :..|:::.|:||:.|....|||::||.|||:|:.::|..||:.|.||||:|.:  |:.....|.:
Mosquito   169 VCCILVLTFINCWDVKWATAVQDIFTYAKLLALFIIIGAGAYYLFQGNTEHFT--FDNTKTEVTS 231

  Fly   275 IATAFYTGLWAYDGWNNLNYVTEEIKNPSKNLPRSIIIGIPLVTLCYALINISYLAAMSPQEMIE 339
            :|.:||:||:||:|||.||::.||:|:|.|||||:|.|...|||:.|...|:|:...:||:|::.
Mosquito   232 LALSFYSGLFAYNGWNYLNFIIEELKDPVKNLPRAIAISCTLVTVVYVFTNVSFYTILSPEEVLG 296

  Fly   340 SEAVAVTFGNRILGALAWLMPLSVTISTFGSANGTLFAAGRLCFAASREGHLLDILSYVHVRRLT 404
            ||||||||.:|:.|..||.:|:.|.:||||:.||.|..:.||.:|.:.||.:.:||:.:.::|||
Mosquito   297 SEAVAVTFADRVFGMFAWTIPVFVALSTFGAVNGILLTSSRLFYAGACEGQMPEILTMIQIQRLT 361

  Fly   405 PAPGLIFHSLIASAMVLHGTIDSLIDFFSFTAWIFYGGAMLALIVMRYTKPNYPRPYKVPIIIPV 469
            |.|.::..:|::...:....|.:||::..|..|:..|.|:|.|..:|:.:|...||.||.:|.|:
Mosquito   362 PTPAVLIMALLSMLYLTVSDIFALINYVGFATWLSIGAAVLCLPWLRWKQPKLNRPIKVNLIFPI 426

  Fly   470 VVLVISVYLVAAPIFETPRVEYLYALLFIFAGLIFYVPFVKLGMTPRFMNK----VTLFFQLLLE 530
            :.|:.:|::...|:..:| ||..|..|.|.:.:..|..|:.....|::.|:    :|...|.|:.
Mosquito   427 LYLIATVFVTVVPMIASP-VETGYGCLMILSSIPVYFIFIAWRNKPKWFNRSMGGITQSLQKLMM 490

  Fly   531 VV 532
            ||
Mosquito   491 VV 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sbm	NP_727785.1	2A0308	53..532	CDD:273332	182/455 (40%)
AgaP_AGAP001627	XP_321470.3	2A0308	37..496	CDD:273332	184/457 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X75
TreeFam	0	0.000	Not matched by this tool.
	5	4.820