DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sbm and AgaP_AGAP011386

DIOPT Version :9

Sequence 1:	NP_727785.1	Gene:	sbm / 32397	FlyBaseID:	FBgn0030574	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	XP_317936.4	Gene:	AgaP_AGAP011386 / 1278313	VectorBaseID:	AGAP011386	Length:	501	Species:	Anopheles gambiae

Alignment Length:	479	Identity:	197/479 - (41%)
Similarity:	296/479 - (61%)	Gaps:	12/479 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 TEGPEAPETDSSGTGRMRKPLERNGSTQNHVVHLERRLGLFSGVALIVGTMIGSGIFVSPSGLLV 111
            |.|..||     ||...|.|....|..    :.:::.|||..|||:|||.::|:||||||.|:|:
Mosquito    17 TTGCFAP-----GTPMGRTPDAGGGGG----IEMKKELGLMDGVAIIVGVIVGAGIFVSPKGVLL 72

  Fly   112 RTGSVGVSFIIWLACGVLSLLGALAYAELGTMNTSSGAEWAYFMDAYGPAPAFLFSWVSTLVLKP 176
            .:||:||:.|:|:..||||::|||.|||||||...||.::||..:|:||.||||:.||:.|:|.|
Mosquito    73 YSGSIGVAIIVWILSGVLSMVGALCYAELGTMIPKSGGDYAYIGEAFGPLPAFLYLWVALLILVP 137

  Fly   177 SQMAIICLSFAQYAVEAFVTECDPPRGVVKMVALVAIVMILFVNCYSVNLGMAVQNVFTAAKLVA 241
            :..||..::||||.::.....|:||...|:::|.|...::..:||.:|.....|...||..|::|
Mosquito   138 AGNAITAITFAQYLLQPLWPTCEPPYESVRLLAAVITCLLTAINCRNVKWVARVTETFTGMKVLA 202

  Fly   242 VVVVICGGAWKLMQGNTQHLSNAFNGPMPNVGAIATAFYTGLWAYDGWNNLNYVTEEIKNPSKNL 306
            ::|:...|||.||.|||:.|...|.......|.||.|||.||::|.|||.||:||||:|:|.:||
Mosquito   203 LLVITGAGAWHLMSGNTELLEAPFANSKIQPGFIAVAFYNGLFSYSGWNYLNFVTEELKDPYRNL 267

  Fly   307 PRSIIIGIPLVTLCYALINISYLAAMSPQEMIESEAVAVTFGNRILGALAWLMPLSVTISTFGSA 371
            ||:|.|.:|:||:.|.:.||:|.|.:.|.||:.|:||||||..::|..:||.|||.|..|||||.
Mosquito   268 PRAICISMPVVTVIYVITNIAYFAVLPPDEMLSSQAVAVTFAEKMLSFMAWTMPLFVACSTFGSL 332

  Fly   372 NGTLFAAGRLCFAASREGHLLDILSYVHVRRLTPAPGLIFHSLIASAMVLHGTIDSLIDFFSFTA 436
            ||.:||:.||.|..:|.|||...||.:::..|||.|.|:|...:...::....:.::|::.|:..
Mosquito   333 NGAIFASSRLFFVGARNGHLPAALSLININCLTPIPSLLFLCALTLLLLFIRDVFAIINYVSYVE 397

  Fly   437 WIFYGGAMLALIVMRYTKPNYPRPYKVPIIIPVVVLVISVYLVAAPIFETPRVEYLYALLFIFAG 501
            .:|...::..|:.:|...|:..||.||.:|:|:|.|:.:.:||...:||:| :|.....|.|..|
Mosquito   398 ILFIFISVAGLLRLRQKAPDAHRPIKVSLIVPIVFLLTAGFLVIFSVFESP-MEVGIGTLVILLG 461

  Fly   502 LIFYVPFVKLGMTPRFMNKVTLFF 525
            :..|  :|.:|...|::.:.:..|
Mosquito   462 IPVY--YVTIGKPWRWLTQKSQSF 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sbm	NP_727785.1	2A0308	53..532	CDD:273332	194/473 (41%)
AgaP_AGAP011386	XP_317936.4	2A0308	35..491	CDD:273332	189/456 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820