DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14414 and Rbm18

DIOPT Version :9

Sequence 1:	NP_001285240.1	Gene:	CG14414 / 32394	FlyBaseID:	FBgn0030571	Length:	213	Species:	Drosophila melanogaster
Sequence 2:	NP_080710.1	Gene:	Rbm18 / 67889	MGIID:	1915139	Length:	190	Species:	Mus musculus

Alignment Length:	188	Identity:	64/188 - (34%)
Similarity:	92/188 - (48%)	Gaps:	29/188 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 GNPEEARRIWVGNLDSRITDSICIAPYRFQLLKLMQKCGAIEKFDMLFHKGGPMVGQSRGYAFVT 85
            |:.:|..|:|:||||.:||:        :.||||:||.|.:::||.||||.|.:.||.|||.||.
Mouse    19 GSLQEGHRLWIGNLDPKITE--------YHLLKLLQKFGKVKQFDFLFHKSGALEGQPRGYCFVN 75

  Fly    86 FAQNEGATNALLKLDGTSVGNRSIAVRLA----KNIKYDETQKPKPRLDIPALGTGKREEKVSKT 146
            |...:.|..|:..|:|....::.:.||.|    |...:::..|..|....|:..|...:..:|.|
Mouse    76 FETKQEAEQAIQCLNGKLALSKKLVVRWAHAQVKRYDHNKNDKILPISLEPSSSTEPAQSNLSVT 140

  Fly   147 EAIRAIEAKLKMLERQTDDNLELNTAGRGEANVPFIQRYQFNKDRDGSQRYGKSSAPY 204
            ..|:||||||||:....|            |..|....|.:.|..|     .|.:.||
Mouse   141 AKIKAIEAKLKMMAENPD------------AEYPAAPVYSYFKPPD-----KKRTTPY 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14414	NP_001285240.1	RRM	<22..>126	CDD:223796	40/107 (37%)
CG14414	NP_001285240.1	RRM_RBM18	28..115	CDD:240801	37/90 (41%)
Rbm18	NP_080710.1	LSM_int_assoc	<26..>189	CDD:330438	62/181 (34%)
		RRM_RBM18	26..105	CDD:240801	36/86 (42%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	166..190		6/21 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849746
Domainoid	1	1.000	69	1.000	Domainoid score	I9672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12204
Inparanoid	1	1.050	97	1.000	Inparanoid score	I5008
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60257
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005768
OrthoInspector	1	1.000	-	-		oto95337
orthoMCL	1	0.900	-	-		OOG6_105828
Panther	1	1.100	-	-	LDO	PTHR21245
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R8087
SonicParanoid	1	1.000	-	-		X4747
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.890