DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr8 and Igsf9

DIOPT Version :9

Sequence 1:	NP_001285239.1	Gene:	dpr8 / 32387	FlyBaseID:	FBgn0052600	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_001139272.1	Gene:	Igsf9 / 93842	MGIID:	2135283	Length:	1179	Species:	Mus musculus

Alignment Length:	226	Identity:	53/226 - (23%)
Similarity:	89/226 - (39%)	Gaps:	42/226 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 KTVKLTCRVKNLGNRTVSW-VRHRDIHLLTVGRYTYTSDQRFEAMHSPHAEDWTLRIRYAQRKDS 121
            :.|.|.|..:......|:| .|.:|:.               :.......::.||.||..:|..:
Mouse   152 EAVTLRCVARGSPQPYVTWKFRGQDLG---------------KGQGQVQVQNGTLWIRRVERGSA 201

  Fly   122 GIYECQISTTP-PIGHSVYLNIVEPVTDIIGGPELHINRGSTINLTCIVKFAPEPPPTVIWSHNR 185
            |.|.||.|::. .|.|:..|.::.|...::......:|....::|.|   .|...|..:.:|..:
Mouse   202 GDYTCQASSSEGSITHATQLLVLGPPVIVVPPSNSTVNSSQDVSLAC---RAEAYPANLTYSWFQ 263

  Fly   186 EIIN-FDSPRGGISLVTEKGVLTTSRLLVQKAITQDSGLYTCTPSNA--NPTS----------VR 237
            :.:| |...|    |.:...:|....|.:|.....|:|.|||.|||.  :|.|          .:
Mouse   264 DGVNVFHISR----LQSRVRILVDGSLWLQATQPDDAGHYTCVPSNGFLHPPSASAYLTVLYPAQ 324

  Fly   238 VHIVDGEHPAAMHTGNNG---NSTASQPPVL 265
            |.::..|.|  :.||..|   ....:.||:|
Mouse   325 VTVMPPETP--LPTGMRGVIRCPVRANPPLL 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr8	NP_001285239.1	IG_like	51..131	CDD:214653	17/73 (23%)
		V-set	52..143	CDD:284989	20/86 (23%)
		IG_like	153..238	CDD:214653	23/97 (24%)
		ig	153..232	CDD:278476	21/81 (26%)
Igsf9	NP_001139272.1	IG_like	28..110	CDD:214653
		Ig	136..223	CDD:386229	20/85 (24%)
		Ig_3	227..305	CDD:372822	19/84 (23%)
		Ig	341..404	CDD:386229	3/13 (23%)
		Ig	436..500	CDD:319273
		FN3	508..599	CDD:238020
		FN3	625..715	CDD:238020
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	767..807
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	819..842
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	942..974
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1016..1079
		PDZ-binding	1177..1179
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900