DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr8 and dscama

DIOPT Version :9

Sequence 1:	NP_001285239.1	Gene:	dpr8 / 32387	FlyBaseID:	FBgn0052600	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	XP_021334866.1	Gene:	dscama / 568643	ZFINID:	ZDB-GENE-050310-7	Length:	2025	Species:	Danio rerio

Alignment Length:	208	Identity:	47/208 - (22%)
Similarity:	86/208 - (41%)	Gaps:	48/208 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 ITGLVGKTVKLTCRVKNLGNRTVSWVRHRDIHLLTVGRYTYTSDQRFEAMHSPHAEDWTLRIRYA 116
            :.|.||..|.|:|.|.......:||.|:.|       :....::.|...::..:     |.:...
Zfish   324 VKGSVGSQVSLSCSVTGSDEFELSWYRNGD-------KINTGANIRMNGINKEN-----LVMDGM 376

  Fly   117 QRKDSGIYEC-------------QI---STTPPIGHSVYLNIVEPVTDIIGGPELHINRGSTINL 165
            .:.|.|:|:|             |:   ..||        .|:...::.:.||      ...::|
Zfish   377 AKSDGGVYQCFSRKAKMSAQDFVQVILEDGTP--------KILSAFSEKVVGP------NDFVSL 427

  Fly   166 TCIVKFAPEPPPTVIWSHNREIINFDSPRGGISLVTEKGVLTTSRLLVQKAITQDSGLYTCTPSN 230
            ||.||..|:  |.:.|:.:.|::..||....:..:|.:|.: .|.|.:.....:|||:|.||.:|
Zfish   428 TCHVKGTPQ--PAITWTLDDEVVAKDSRHRIVHSITAEGNV-VSYLNISHIQVRDSGVYRCTCNN 489

  Fly   231 ANPT---SVRVHI 240
            :..|   ..|:::
Zfish   490 SAGTVSYQARINV 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr8	NP_001285239.1	IG_like	51..131	CDD:214653	18/94 (19%)
		V-set	52..143	CDD:284989	20/106 (19%)
		IG_like	153..238	CDD:214653	24/87 (28%)
		ig	153..232	CDD:278476	23/78 (29%)
dscama	XP_021334866.1	Ig	124..217	CDD:325142
		I-set	236..311	CDD:254352
		IG_like	321..402	CDD:214653	18/89 (20%)
		I-set	408..502	CDD:333254	28/110 (25%)
		IGc2	524..579	CDD:197706
		Ig	614..679	CDD:319273
		Ig_DSCAM	708..787	CDD:143211
		Ig	805..898	CDD:325142
		FN3	894..988	CDD:238020
		FN3	995..1092	CDD:238020
		fn3	1100..1186	CDD:306538
		fn3	1199..1282	CDD:306538
		Ig	1312..1377	CDD:319273
		fn3	1405..1471	CDD:306538
		FN3	1492..1563	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810