DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr8 and LSAMP

DIOPT Version :9

Sequence 1:	NP_001285239.1	Gene:	dpr8 / 32387	FlyBaseID:	FBgn0052600	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_001305844.1	Gene:	LSAMP / 4045	HGNCID:	6705	Length:	361	Species:	Homo sapiens

Alignment Length:	271	Identity:	67/271 - (24%)
Similarity:	110/271 - (40%)	Gaps:	66/271 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IIFLGILCLLAGCTDGASKRFFTDFLQDLPTPGTGGP--TFDTTIGT-NITGLVGKTVKLTCRVK 67
            ::.|.:||||.                      ||.|  :.|...|| |||...|.|..|.|.|:
Human    14 LVLLRLLCLLP----------------------TGLPVRSVDFNRGTDNITVRQGDTAILRCVVE 56

  Fly    68 NLGNRTVSWVRHRDIHLLTVGRYTYTSDQRFEAMHSPHAEDWTLRIRYAQRKDSGIYECQISTT- 131
            : .|..|:|:....|  :..|...::.|.|.| :...|:.:::|||:.....|.|.|.|.:.|.
Human    57 D-KNSKVAWLNRSGI--IFAGHDKWSLDPRVE-LEKRHSLEYSLRIQKVDVYDEGSYTCSVQTQH 117

  Fly   132 PPIGHSVYLNIVEP--VTDIIGGPELHINRGSTINLTCIVKFAPEPPPTVIWSH----NREIINF 190
            .|....|||.:..|  :::|  ..::.:|.||.:.|.|:....||  |.:.|.|    .||   |
Human   118 EPKTSQVYLIVQVPPKISNI--SSDVTVNEGSNVTLVCMANGRPE--PVITWRHLTPTGRE---F 175

  Fly   191 DSPRGGISLVTEKGVLTTSRLLVQKAITQD-SGLYTCTPSN----ANPTSVRVHIVDGEHPAAMH 250
            :.....:.::               .||:: ||.|.|..:|    |:...|:|.:   .:|..:.
Human   176 EGEEEYLEIL---------------GITREQSGKYECKAANEVSSADVKQVKVTV---NYPPTIT 222

  Fly   251 TGNNGNSTASQ 261
            ...:..:|..:
Human   223 ESKSNEATTGR 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr8	NP_001285239.1	IG_like	51..131	CDD:214653	24/79 (30%)
		V-set	52..143	CDD:284989	28/91 (31%)
		IG_like	153..238	CDD:214653	22/93 (24%)
		ig	153..232	CDD:278476	20/87 (23%)
LSAMP	NP_001305844.1	Ig	38..128	CDD:386229	30/93 (32%)
		Ig	132..215	CDD:386229	24/104 (23%)
		Ig_3	219..294	CDD:372822	1/15 (7%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810