DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr8 and Lsamp

DIOPT Version :9

Sequence 1:NP_001285239.1 Gene:dpr8 / 32387 FlyBaseID:FBgn0052600 Length:344 Species:Drosophila melanogaster
Sequence 2:XP_038944182.1 Gene:Lsamp / 29561 RGDID:71102 Length:378 Species:Rattus norvegicus


Alignment Length:288 Identity:72/288 - (25%)
Similarity:116/288 - (40%) Gaps:65/288 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MSTHWI-------IFLGILCL--LAGCTDGASKRFFTD-----FLQDLPTPGTGGPTFDTTIGT- 50
            |.|:|:       .||.:..|  ||         |:..     .|..:..||....:.|...|| 
  Rat     1 MRTYWLHSVWVLGFFLSLFSLQVLA---------FWNQPPAEVNLSPITIPGLPVRSVDFNRGTD 56

  Fly    51 NITGLVGKTVKLTCRVKNLGNRTVSWVRHRDIHLLTVGRYTYTSDQRFEAMHSPHAEDWTLRIRY 115
            |||...|.|..|.|.|:: .|..|:|:....|  :..|...::.|.|.| :...||.:::|||:.
  Rat    57 NITVRQGDTAILRCVVED-KNSKVAWLNRSGI--IFAGHDKWSLDPRVE-LEKRHALEYSLRIQK 117

  Fly   116 AQRKDSGIYECQISTT-PPIGHSVYLNIVEP--VTDIIGGPELHINRGSTINLTCIVKFAPEPPP 177
            ....|.|.|.|.:.|. .|....|||.:..|  :::|  ..::.:|.||.:.|.|:....||  |
  Rat   118 VDVYDEGSYTCSVQTQHEPKTSQVYLIVQVPPKISNI--SSDVTVNEGSNVTLVCMANGRPE--P 178

  Fly   178 TVIWSH----NREIINFDSPRGGISLVTEKGVLTTSRLLVQKAITQD-SGLYTCTPSN----ANP 233
            .:.|.|    .||   |:.....:.::               .||:: ||.|.|..:|    |:.
  Rat   179 VITWRHLTPLGRE---FEGEEEYLEIL---------------GITREQSGKYECKAANEVSSADV 225

  Fly   234 TSVRVHIVDGEHPAAMHTGNNGNSTASQ 261
            ..|:|.:   .:|..:....:..:|..:
  Rat   226 KQVKVTV---NYPPTITESKSNEATTGR 250

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr8NP_001285239.1 IG_like 51..131 CDD:214653 25/79 (32%)
V-set 52..143 CDD:284989 29/91 (32%)
IG_like 153..238 CDD:214653 22/93 (24%)
ig 153..232 CDD:278476 20/87 (23%)
LsampXP_038944182.1 Ig 55..145 CDD:416386 31/93 (33%)
FR1 55..71 CDD:409353 7/15 (47%)
Ig strand A' 56..62 CDD:409353 3/5 (60%)
Ig strand B 64..72 CDD:409353 3/7 (43%)
CDR1 72..76 CDD:409353 1/4 (25%)
FR2 77..84 CDD:409353 2/6 (33%)
Ig strand C 77..83 CDD:409353 2/5 (40%)
CDR2 85..95 CDD:409353 2/11 (18%)
Ig strand C' 87..90 CDD:409353 1/4 (25%)
Ig strand C' 92..95 CDD:409353 0/2 (0%)
FR3 96..131 CDD:409353 12/35 (34%)
Ig strand D 100..107 CDD:409353 2/7 (29%)
Ig strand E 110..116 CDD:409353 2/5 (40%)
Ig strand F 123..131 CDD:409353 3/7 (43%)
CDR3 132..136 CDD:409353 1/3 (33%)
Ig strand G 136..145 CDD:409353 4/8 (50%)
FR4 138..145 CDD:409353 3/6 (50%)
Ig_3 148..218 CDD:404760 21/91 (23%)
Ig strand A' 155..160 CDD:409353 0/4 (0%)
Ig strand B 166..173 CDD:409353 2/6 (33%)
Ig strand C 179..184 CDD:409353 1/4 (25%)
Ig strand D 190..193 CDD:409353 2/5 (40%)
Ig strand E 197..203 CDD:409353 0/20 (0%)
Ig strand F 210..217 CDD:409353 3/6 (50%)
Ig strand G 224..232 CDD:409353 2/7 (29%)
Ig_3 235..311 CDD:404760 2/16 (13%)
Ig strand B 252..256 CDD:409353
Ig strand C 265..269 CDD:409353
Ig strand E 290..294 CDD:409353
Ig strand F 304..309 CDD:409353
Ig strand G 318..321 CDD:409353
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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