DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr8 and Sdk2

DIOPT Version :9

Sequence 1:NP_001285239.1 Gene:dpr8 / 32387 FlyBaseID:FBgn0052600 Length:344 Species:Drosophila melanogaster
Sequence 2:NP_766388.2 Gene:Sdk2 / 237979 MGIID:2443847 Length:2176 Species:Mus musculus


Alignment Length:207 Identity:50/207 - (24%)
Similarity:78/207 - (37%) Gaps:51/207 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    42 PTFDTTIGTNITGLVGKTVKLTCRVKNLGNRTVSWVRHRDIHLLTVGRYTYTSDQRFEAMHSPHA 106
            |.|......:||..:.|.|.:.||.|.:...:::|  ::|..|:.||:.|               
Mouse   312 PQFVREPERHITAEMEKVVDIPCRAKGVPPPSITW--YKDAALVEVGKLT--------------- 359

  Fly   107 EDWTLRIRYAQRKDSGIYECQISTTPP--------IGH--------SVYLNIVEPVTDIIGGP-E 154
                   |:.||.|.|:   |||...|        ..|        |.||.:.....:|..|| :
Mouse   360 -------RFKQRSDGGL---QISGLLPDDTGMLQCFAHNAAGEAQTSTYLAVTSIAPNITRGPLD 414

  Fly   155 LHINRGSTINLTCIVKFAPEPPPTVIWSHNREIINFDSPRGGISLVTEKGVLTTSRLLVQKAITQ 219
            ..:..|.::.|.|....||.  |.:.|.....|:    ..|.:.| ....:|.:..||:......
Mouse   415 STVIDGMSVVLACETSGAPR--PAITWQKGERIL----ASGSVQL-PRFTLLESGSLLISPTHIS 472

  Fly   220 DSGLYTCTPSNA 231
            |:|.|||..:|:
Mouse   473 DAGTYTCLATNS 484

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr8NP_001285239.1 IG_like 51..131 CDD:214653 21/79 (27%)
V-set 52..143 CDD:284989 26/106 (25%)
IG_like 153..238 CDD:214653 20/80 (25%)
ig 153..232 CDD:278476 20/80 (25%)
Sdk2NP_766388.2 IG_like 44..113 CDD:214653
IGc2 44..102 CDD:197706
IG_like 124..207 CDD:214653
Ig 136..192 CDD:299845
IG_like 226..308 CDD:214653
IGc2 237..290 CDD:197706
I-set 312..401 CDD:254352 28/115 (24%)
Ig 330..398 CDD:143165 21/94 (22%)
I-set 406..496 CDD:254352 22/86 (26%)
Ig 420..496 CDD:299845 19/72 (26%)
Ig 506..590 CDD:299845
IG_like 506..590 CDD:214653
FN3 594..685 CDD:238020
FN3 697..790 CDD:238020
FN3 798..894 CDD:238020
FN3 899..987 CDD:238020
FN3 997..1091 CDD:238020
FN3 1103..1198 CDD:238020
FN3 1205..1294 CDD:238020
FN3 1305..1398 CDD:238020
FN3 1404..1488 CDD:238020
FN3 1507..1620 CDD:238020
FN3 1630..1723 CDD:238020
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1712..1734
FN3 1728..1809 CDD:238020
FN3 1841..1920 CDD:238020
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2013..2032
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2043..2070
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2102..2176
PDZ-binding. /evidence=ECO:0000269|PubMed:20219992 2170..2176
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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