DRSC/TRiP Functional Genomics Resources

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Protein Alignment dpr8 and Ntm

DIOPT Version :9

Sequence 1:NP_001285239.1 Gene:dpr8 / 32387 FlyBaseID:FBgn0052600 Length:344 Species:Drosophila melanogaster
Sequence 2:NP_001344522.1 Gene:Ntm / 235106 MGIID:2446259 Length:367 Species:Mus musculus


Alignment Length:275 Identity:75/275 - (27%)
Similarity:107/275 - (38%) Gaps:71/275 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 STHWIIFLGI--LCLLAGCTDGASKRFFTDFLQDLPTPGTGGPTFDTTIGTNITGLVGKTVKLTC 64
            |..|.||.|:  |||..|                :|. .:|..||...: .|:|...|::..|.|
Mouse    11 SISWAIFTGLAALCLFQG----------------VPV-RSGDATFPKAM-DNVTVRQGESATLRC 57

  Fly    65 RVKNLGNRTVSWVRHRDIHLLTVGRYTYTSDQRFEAMHSPHAEDWTLRIRYAQRKDSGIYECQIS 129
            .:.|...| |:|:....|  |..|...:..|.|...:.:...: :::.|:.....|.|.|.|.:.
Mouse    58 TIDNRVTR-VAWLNRSTI--LYAGNDKWCLDPRVVLLSNTQTQ-YSIEIQNVDVYDEGPYTCSVQ 118

  Fly   130 T-TPPIGHSVYL------NIVEPVTDIIGGPELHINRGSTINLTCIVKFAPEPPPTVIWSHNREI 187
            | ..|....|:|      .|||..:||      .||.|:.|:||||....||  |||.|.|    
Mouse   119 TDNHPKTSRVHLIVQVSPKIVEISSDI------SINEGNNISLTCIATGRPE--PTVTWRH---- 171

  Fly   188 INFDSPRGGISLVTEKGVLTTSRLLVQKAITQDSGLYTCTPSN--ANPTSVRVHIVDGEHPAAMH 250
               .||: .:..|:|...|.     :|....:.||.|.|:.||  |.|...||.:          
Mouse   172 ---ISPK-AVGFVSEDEYLE-----IQGITREQSGEYECSASNDVAAPVVRRVKV---------- 217

  Fly   251 TGNNGNSTASQPPVL 265
                   |.:.||.:
Mouse   218 -------TVNYPPYI 225

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dpr8NP_001285239.1 IG_like 51..131 CDD:214653 20/80 (25%)
V-set 52..143 CDD:284989 22/97 (23%)
IG_like 153..238 CDD:214653 29/86 (34%)
ig 153..232 CDD:278476 27/80 (34%)
NtmNP_001344522.1 Ig 44..132 CDD:416386 23/91 (25%)
Ig strand A' 44..49 CDD:409353 2/4 (50%)
Ig strand B 51..59 CDD:409353 2/7 (29%)
CDR1 59..63 CDD:409353 1/3 (33%)
FR2 64..70 CDD:409353 3/6 (50%)
Ig strand C 64..70 CDD:409353 3/6 (50%)
CDR2 71..83 CDD:409353 3/13 (23%)
Ig strand C' 72..76 CDD:409353 1/5 (20%)
Ig strand C' 80..83 CDD:409353 0/2 (0%)
FR3 84..118 CDD:409353 7/34 (21%)
Ig strand D 87..94 CDD:409353 1/6 (17%)
Ig strand E 97..103 CDD:409353 0/6 (0%)
Ig strand F 110..118 CDD:409353 3/7 (43%)
CDR3 119..123 CDD:409353 1/3 (33%)
Ig strand G 123..132 CDD:409353 3/8 (38%)
FR4 125..132 CDD:409353 2/6 (33%)
Ig_3 136..205 CDD:404760 30/89 (34%)
Ig strand A' 144..148 CDD:409353 2/9 (22%)
Ig strand B 151..160 CDD:409353 5/8 (63%)
Ig strand F 197..205 CDD:409353 3/7 (43%)
Ig_3 222..299 CDD:404760 2/4 (50%)
putative Ig strand A 223..229 CDD:409353 1/3 (33%)
Ig strand B 239..243 CDD:409353
Ig strand C 252..256 CDD:409353
Ig strand E 278..282 CDD:409353
Ig strand F 292..297 CDD:409353
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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