DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dpr8 and igcm-2

DIOPT Version :9

Sequence 1:	NP_001285239.1	Gene:	dpr8 / 32387	FlyBaseID:	FBgn0052600	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	NP_001362087.1	Gene:	igcm-2 / 180913	WormBaseID:	WBGene00020130	Length:	802	Species:	Caenorhabditis elegans

Alignment Length:	310	Identity:	77/310 - (24%)
Similarity:	110/310 - (35%)	Gaps:	92/310 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 GLVGKTVKLTCRVKNLGNRTVSWVRHRDIHLL------TVGRYTYTSDQRFEAMHSPHAEDWTL- 111
            |..|..:.|.|.:......:.|....:|..|:      ..|..|.|...|.       |.|..|
Worm    25 GKAGAPITLPCSISLFNEESFSLDWRKDGQLILSAFGQEQGHVTPTLQGRL-------ARDGFLG 82

  Fly   112 -RIRYAQRKDSGIYECQIS------TTPPIGHSVYLNIVEPVTDIIGGPE----LHINRGSTINL 165
             .|......|:|:|:|.::      |.|..|.|.  .:|..|..:|..|.    :|...|:.:..
Worm    83 ITIHSVTDGDAGVYQCIVTKFSKQPTRPEKGLSA--KLVVNVPPVIISPSKNAIIHKKVGADLIF 145

  Fly   166 TCIVKFAPEPPPTVIWSHNREIINFDSPRGGISLVTEKGVLTTSRLLVQKAITQDSGLYTCTPSN 230
            .|..:.||.  |.:.||.|.:||: .||           |||.|.|     ...|.|||||...|
Worm   146 ECKAEGAPS--PEITWSRNEQIIS-TSP-----------VLTLSNL-----EEGDKGLYTCLAVN 191

  Fly   231 ANPTSVRVHIVDGEHPAAMHTGNNGNSTASQPPVLLPLVLLTCSTLMLLQLVASCSTLVPATPP- 294
            .                      .||||:|..      |..|.:|  :|.|:....|::..:..
Worm   192 I----------------------EGNSTSSID------VRFTKAT--ILDLIPLNKTVIEGSNVF 226

  Fly   295 -GCRTVQQASTFA-----EEK-----AMGQRSNRNCQDLQELEESQDLRR 333
             .|....||:..:     |:|     ::|.|||....||    ..||:|:
Worm   227 WHCHANAQATAISYSWLFEKKPIKTTSLGLRSNIRSGDL----SLQDVRK 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dpr8	NP_001285239.1	IG_like	51..131	CDD:214653	19/90 (21%)
		V-set	52..143	CDD:284989	23/102 (23%)
		IG_like	153..238	CDD:214653	26/88 (30%)
		ig	153..232	CDD:278476	26/82 (32%)
igcm-2	NP_001362087.1	IG_like	23..101	CDD:214653	19/82 (23%)
		Ig	124..200	CDD:386229	31/116 (27%)
		IG_like	214..298	CDD:214653	15/63 (24%)
		Ig_3	309..371	CDD:372822
		Ig	389..467	CDD:386229
		FN3	476..548	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900