DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9400 and CRISPLD2

DIOPT Version :9

Sequence 1:	NP_572957.1	Gene:	CG9400 / 32385	FlyBaseID:	FBgn0030562	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_113664.1	Gene:	CRISPLD2 / 83716	HGNCID:	25248	Length:	497	Species:	Homo sapiens

Alignment Length:	234	Identity:	62/234 - (26%)
Similarity:	92/234 - (39%)	Gaps:	65/234 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 CGNNGSFSPACGPEPKLLEM-------SERRRQL-------LLDMHNLARSKIASGNLDGYRSAA 122
            ||:.|...|......:||..       |..||.:       :|.:||..|.::..       .|:
Human    18 CGSQGYLLPNVTLLEELLSKYQHNESHSRVRRAIPREDKEEILMLHNKLRGQVQP-------QAS 75

  Fly   123 HMPLLRWDTELEQMAALHAKRCQFAHDKCRNTPRFKFSGQNIGYFWIGREFKSHSRRMKSFVINW 187
            :|..:.||.|||:.||..|.:|.:.|..   |......|||:|..| || ::|....::|    |
Human    76 NMEYMTWDDELEKSAAAWASQCIWEHGP---TSLLVSIGQNLGAHW-GR-YRSPGFHVQS----W 131

  Fly   188 FREHQDANQSFIDRYHPHP-----------QGKKIGHFTLLVSDRVNRVGCA----------GVR 231
            :.|.:|..       :|:|           .|....|:|.:|....|::|||          |
Human   132 YDEVKDYT-------YPYPSECNPWCPERCSGPMCTHYTQIVWATTNKIGCAVNTCRKMTVWG-- 187

  Fly   232 FLEPKSNRFQFMLTCNYD-YNNIFNEPIYQSGPAGSKCP 269
              |...|...|:  |||. ..|...|..|::|...|:||
Human   188 --EVWENAVYFV--CNYSPKGNWIGEAPYKNGRPCSECP 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9400	NP_572957.1	SCP_euk	96..249	CDD:240180	46/180 (26%)
CRISPLD2	NP_113664.1	SCP_euk	56..201	CDD:240180	45/173 (26%)
		LCCL	286..370	CDD:128866
		LCCL	387..479	CDD:128866
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151227
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X35
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.950