DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9400 and CRISPLD1

DIOPT Version :9

Sequence 1:	NP_572957.1	Gene:	CG9400 / 32385	FlyBaseID:	FBgn0030562	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_113649.1	Gene:	CRISPLD1 / 83690	HGNCID:	18206	Length:	500	Species:	Homo sapiens

Alignment Length:	195	Identity:	57/195 - (29%)
Similarity:	87/195 - (44%)	Gaps:	39/195 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 MSERRRQLLLDMHNLARSKIASGNLDGYRSAAHMPLLRWDTELEQMAALHAKRCQFAHDKCRNTP 155
            :::...|.:||:||..||::       |.:|::|..:.||.|||:.|...|:.|.:.|......|
Human    57 ITDNDMQSILDLHNKLRSQV-------YPTASNMEYMTWDVELERSAESWAESCLWEHGPASLLP 114

  Fly   156 RFKFSGQNIGYFWIGREFKSHSRRMKSF-VINWFREHQDANQSFIDRYHPH-P---QGKKIGHFT 215
            ..   |||:|..| ||      .|..:| |.:|:.|.:|.:..:....:|: |   .|....|:|
Human   115 SI---GQNLGAHW-GR------YRPPTFHVQSWYDEVKDFSYPYEHECNPYCPFRCSGPVCTHYT 169

  Fly   216 LLVSDRVNRVGCA----------GVRFLEPKSNRFQFMLTCNYD-YNNIFNEPIYQSGPAGSKCP 269
            .:|....||:|||          |.  :.||:    ..|.|||. ..|.:....|:.|...|.||
Human   170 QVVWATSNRIGCAINLCHNMNIWGQ--IWPKA----VYLVCNYSPKGNWWGHAPYKHGRPCSACP 228

Fly 270 269
Human 229 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9400	NP_572957.1	SCP_euk	96..249	CDD:240180	50/167 (30%)
CRISPLD1	NP_113649.1	SCP_euk	63..207	CDD:240180	50/166 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	254..281
		LCCL	291..375	CDD:128866
		LCCL	392..483	CDD:128866
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151164
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X35
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.950