DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9400 and CLEC18B

DIOPT Version :9

Sequence 1:	NP_572957.1	Gene:	CG9400 / 32385	FlyBaseID:	FBgn0030562	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_001011880.2	Gene:	CLEC18B / 497190	HGNCID:	33849	Length:	455	Species:	Homo sapiens

Alignment Length:	214	Identity:	54/214 - (25%)
Similarity:	73/214 - (34%)	Gaps:	68/214 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 PKLLE-------MSERRRQLLLDMHNLARSKIASGNLDGYRSAAHMPLLRWDTELEQMAALHAKR 143
            |:|.|       ::.:...|||.:||..||.:..       .||.|..|.|...|.|:|...|..
Human    31 PQLQEQAPMAGALNRKESFLLLSLHNRLRSWVQP-------PAADMRRLDWSDSLAQLAQARAAL 88

  Fly   144 CQFAHDKCRNTPRFKFSGQNIGYFW----IGREFKSHSRRMKSF---VINWFREHQDANQSFIDR 201
            |...      ||... ||     .|    :|...:.....:.||   |..||.|.|        |
Human    89 CGIP------TPSLA-SG-----LWRTLQVGWNMQLLPAGLASFVEVVSLWFAEGQ--------R 133

  Fly   202 YHPHPQGK-----KIGHFTLLVSDRVNRVGC------AGVRFLEPKSNRFQFMLTC------NYD 249
            | .|..|:     ...|:|.||....:::||      ||...:|        ...|      |::
Human   134 Y-SHAAGECARNATCTHYTQLVWATSSQLGCGRHLCSAGQTAIE--------AFVCAYSPGGNWE 189

  Fly   250 YNNIFNEPIYQSGPAGSKC 268
            .|.....| |:.|...|.|
Human   190 VNGKTIIP-YKKGAWCSLC 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9400	NP_572957.1	SCP_euk	96..249	CDD:240180	45/176 (26%)
CLEC18B	NP_001011880.2	SCP_euk	50..183	CDD:240180	44/168 (26%)
CLEC18B	NP_001011880.2	CLECT	310..443	CDD:153057
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151055
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.850