DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9400 and PI16

DIOPT Version :9

Sequence 1:	NP_572957.1	Gene:	CG9400 / 32385	FlyBaseID:	FBgn0030562	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_001186088.1	Gene:	PI16 / 221476	HGNCID:	21245	Length:	463	Species:	Homo sapiens

Alignment Length:	213	Identity:	56/213 - (26%)
Similarity:	97/213 - (45%)	Gaps:	37/213 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 MSERRRQLLLDMHNLARSKIASGNLDGYRSAAHMPLLRWDTELEQMAALHAKRCQFAHDKCRNTP 155
            :::..::|::::|||.|::::.       :|:.|..:|||.||...|..:|::|.:.|:|.|..
Human    28 LTDEEKRLMVELHNLYRAQVSP-------TASDMLHMRWDEELAAFAKAYARQCVWGHNKERGR- 84

  Fly   156 RFKFSGQNIGYFWIGREFKSHSRRMKSFVINWFREHQDANQSFIDRYHPHPQGKKIGHFTLLVSD 220
                .|:|:  |.|..|.......|:    .|..|.:..|.|..    ....|:..||:|.:|..
Human    85 ----RGENL--FAITDEGMDVPLAME----EWHHEREHYNLSAA----TCSPGQMCGHYTQVVWA 135

  Fly   221 RVNRVGCAGVRFLEP----KSNRFQFMLTCNYD-YNNIFNEPIYQSGPAGSKCPQHRISEKFPSL 280
            :..|:|| |..|.|.    :....: :|.|||: ..|:..:..||.|...|:||.....:.  ||
Human   136 KTERIGC-GSHFCEKLQGVEETNIE-LLVCNYEPPGNVKGKRPYQEGTPCSQCPSGYHCKN--SL 196

  Fly   281 CDWRDANNDLDSEESDED 298
            |:      .:.|.|..:|
Human   197 CE------PIGSPEDAQD 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9400	NP_572957.1	SCP_euk	96..249	CDD:240180	42/156 (27%)
PI16	NP_001186088.1	SCP_HrTT-1	33..166	CDD:240186	42/156 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	262..281
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	303..341
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	383..408
		O-glycosylated at one site	386..395
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3709
SonicParanoid	1	1.000	-	-		X35
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	5.050