DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9400 and vap-2

DIOPT Version :9

Sequence 1:	NP_572957.1	Gene:	CG9400 / 32385	FlyBaseID:	FBgn0030562	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_001300377.1	Gene:	vap-2 / 181273	WormBaseID:	WBGene00011462	Length:	507	Species:	Caenorhabditis elegans

Alignment Length:	259	Identity:	74/259 - (28%)
Similarity:	107/259 - (41%)	Gaps:	54/259 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 CAAALCELYNGTHLVHVPHTAC-------GNNGSFSPACGPEPKLLEMSERRRQLLLDMHNLARS 108
            |....|..|.|:..: ||...|       .:.|||.  |  :..|  :|:..|...|:.||..||
Worm   271 CEDKDCFTYPGSKCL-VPEGLCQAPSMVKDDGGSFQ--C--DNSL--VSDVTRNFTLEQHNFYRS 328

  Fly   109 KIASG---NLDGYRS---AAHMPLLRWDTELEQMAALHAKRCQFAHDKCRNTPRFKFSGQNIGYF 167
            ::|.|   |.:...|   |:.|..:.:|..||:.|...|..|.|||......|.   .|||: |.
Worm   329 RLAKGFEWNGETNTSQPKASQMIKMEYDCMLERFAQNWANNCVFAHSAHYERPN---QGQNL-YM 389

  Fly   168 WIGREFKSHSRR--MKSFVINWFREHQDANQSFIDRYHPH---PQGKKIGHFTLLVSDRVNRVGC 227
               ..|.:...|  :.:.|..|::|.::......:...|.   .:||.|||:|.:..||..|:||
Worm   390 ---SSFSNPDPRSLIHTAVEKWWQELEEFGTPIDNVLTPELWDLKGKAIGHYTQMAWDRTYRLGC 451

  Fly   228 AGVRFLEPKSNRFQFMLTCNY-DYNNIFNEPIYQSG---------PAGSKCPQHRISEKFPSLC 281
             |:... ||.:    .:.|:| ...|..|..||:.|         |.|:.|      ||..|||
Worm   452 -GIANC-PKMS----YVVCHYGPAGNRKNNKIYEIGDPCEVDDDCPIGTDC------EKTTSLC 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9400	NP_572957.1	SCP_euk	96..249	CDD:240180	48/164 (29%)
vap-2	NP_001300377.1	SCP	104..253	CDD:214553
vap-2	NP_001300377.1	SCP	315..468	CDD:214553	48/165 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1528782at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14643
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10334
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X35
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.020