DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Muc12Ea and clec-122

DIOPT Version :9

Sequence 1:	NP_001368944.1	Gene:	Muc12Ea / 32384	FlyBaseID:	FBgn0052602	Length:	3321	Species:	Drosophila melanogaster
Sequence 2:	NP_494447.1	Gene:	clec-122 / 189536	WormBaseID:	WBGene00021290	Length:	605	Species:	Caenorhabditis elegans

Alignment Length:	421	Identity:	102/421 - (24%)
Similarity:	135/421 - (32%)	Gaps:	67/421 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 TSSSRATTPKPTLETTIGTTFKTTQITTRGPTTQKPTEGTSAQPTTLKPTEGTTAKPTTLKPTEG 160
            ||:|..||      ||:.:       |:.|.||.....|.|...|.   ..|:||.......|..
Worm    24 TSTSTVTT------TTVAS-------TSSGSTTASTAAGGSTSTTA---AGGSTASTAAGGSTST 72

  Fly   161 TTAKPTTLKPTEGTSAKPTTLKPTEGTTAKPTTLKPTEGTSAKPTTLKPTEGTTAKPTTLKPTEG 225
            |.|..:|:....|.|        |..|.|..:|.....|.|...|....:..|||       ..|
Worm    73 TAAGGSTVSTAAGGS--------TASTAAGGSTASTAAGGSTATTAAGGSTATTA-------AGG 122

  Fly   226 TTAKPTTLKPTEGTTAKPTTLKPTEGTSAKPTTLKPTEGTTAKPTTLKPTEGTSAKPTTLKPTEG 290
            :||.......|..|.|..:|.....|.|        |..|.|..:|.....|.|...|....:..
Worm   123 STASTAAGGSTATTAAGGSTASTAAGGS--------TASTAAGGSTASTAAGGSTATTAAGGSTA 179

  Fly   291 TTAKPTTLKPTEGTTAKPTTLKPTEGTSAKPTTLKPTEGTTAKPTTLKPTEGTSAKPTTLKPTEG 355
            |||       ..|:||.......|..|:|..:|.....|.:...|....:..|:|       ..|
Worm   180 TTA-------AGGSTASTAAGGSTATTAAGGSTASTAAGGSTASTAAGGSTATTA-------AGG 230

  Fly   356 TTAKPTTLKPTEGTSAKPTTLKPTEGTSAKPTTLKPTEGTSAKPTTLKPTEGTSAKPTTLKPTEG 420
            :||.......|..|:|..:|.....|.|...|.   ..|::|.......|..|:|..:|.....|
Worm   231 STATTAAGGSTASTAAGGSTASTAAGGSTATTA---AGGSTATTAAGGSTASTAAGGSTATTAAG 292

  Fly   421 TSAKPTTLKPTAGTTAKPTTLKPTEGTSAKPTTLKPTEGTTAKPTTLKPTEGTTAKPTTLKPTEG 485
            .|        ||.|.|..:|.....|.|...|.   ..|:||.......|..|.|..:|.....|
Worm   293 GS--------TASTAAGGSTASTAAGGSTATTA---AGGSTATTAAGGSTASTAAGGSTASTAAG 346

  Fly   486 TSAKPTTLKPTEGTTAKPTTLKPTEGTSAQP 516
            .|...|....:..:|.......|....:.:|
Worm   347 GSTATTAAGGSTASTGVTVASSPAPAAACEP 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Muc12Ea	NP_001368944.1	PHA03247	<175..670	CDD:223021	80/342 (23%)
		PHA03247	<659..1197	CDD:223021
		PHA03247	<1049..1651	CDD:223021
		PHA03247	<1723..2186	CDD:223021
		PHA03247	<2110..2706	CDD:223021
clec-122	NP_494447.1	PRK08026	<94..351	CDD:236140	72/299 (24%)
		CLECT	375..505	CDD:214480	1/3 (33%)
		CLECT	550..>599	CDD:214480
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14552
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000