Protein Alignment Muc12Ea and dpy-6

DIOPT Version :9

• Sequence 1: NP_001368944.1
• Gene: Muc12Ea / 32384
• FlyBaseID: FBgn0052602
• Length: 3321
• Species: Drosophila melanogaster
• Sequence 2: NP_509435.2
• Gene: dpy-6 / 181099
• WormBaseID: WBGene00001068
• Length: 1254
• Species: Caenorhabditis elegans
• Alignment Length: 1183
• Identity: 375/1183 - (31%)
• Similarity: 490/1183 - (41%)
• Gaps: 288/1183 - (24%)

  Fly   741 KPTEGTSAQPTTLKPTEG---TTAKPTTLKPTEGTSAQPTTLKPTKGTTAKPTTLKPTEGTSAKP 802
            |.|..|.|. ||..||.|   ||.:..|......:.::..|   ...||...|||.||......|
 Worm   119 KVTTSTDAS-TTNAPTTGKDSTTPEIITGIVVINSKSESVT---DMSTTRFSTTLSPTTELLTSP 179

  Fly   803 TTLKPTEGTTAKPTTLKPTEGTSAKPTT--LKPTEGTTAKPTTLKPTEGTTAKPTTLKPTDGTTA 865
            .||..|:.:|:       ||.||...||  ..|.|..|.       ||.||   |:::|:..|.|
 Worm   180 ETLVSTDSSTS-------TEQTSPDNTTEIASPMETNTT-------TEATT---TSVEPSVSTLA 227

  Fly   866 KPTTLKPTEGTSAKPTTLKP-TEGTTAKPTTLKPTEGTTAKPTTLKPTDGTTAKPTTLKPTEGTS 929
                       |...||:.. .|.||   |.:.....||.:||       |||:.||.|.|  |.
 Worm   228 -----------SEDETTVTAIAESTT---TVIAEVSTTTEEPT-------TTAESTTKKST--TK 269

  Fly   930 AKPTTLKPTDGTTAKSTTLKPTEGTSAKPTTLKPTEGTTAKPTTLKP-TEGTTAKPTTLKPTEGT 993
            |..||.:||..||.:.||      |.|:.:|...:|.:|.||||  | .:...|.|.|.||
 Worm   270 APATTEEPTPTTTEEVTT------TEAETSTTTSSETSTEKPTT--PLIDNKIAGPATGKP---- 322

  Fly   994 SAKPTTLKPTEGTTAK--PTTLKPTEGTSAQPTTLKPTEGTSAKPTTLKPTDGTTAKPTTLKPTE 1056
               .||..|..|||..  ..|..|....|....||..|..|.....|.:.|||         |.:
 Worm   323 ---ETTHFPVTGTTPNFDTATETPFVAKSEDKMTLSKTAATETTQQTTEVTDG---------PEK 375

  Fly  1057 GTSAKPTTLKPTEGTTAKPTTLKPTEGTSAKPTTLKPTEG--TTAKPTTLKPTEGTTAKPTTLKP 1119
            .|:...:...|.       ||:...|.||...|..|.::|  ||.|.........:|...||:||
 Worm   376 ETTKNVSIEIPI-------TTVPLVETTSTTSTASKESDGFHTTLKLKVTTADSDSTESATTVKP 433

  Fly  1120 -TEGTTAKPTTL-KPTEGTSAKPTTL------KPTEGTTAKPTTLKPTEGTTAKPTTLKPTEGTS 1176
             .|.||.|...: |||:..:.|.|..      :|||.|.| |..:||.:.||   ||      ||
 Worm   434 FNEETTTKSHVVPKPTKKGTVKVTPKLELSFDEPTEITKA-PHPVKPRKTTT---TT------TS 488

  Fly  1177 AKPTTLKP--TEGTTA--KPTTLNQLRERVPSQHFEPTEGTTAKPTTLKPTEGTTAKPTTLKPTK 1237
            ...||.||  |||:|.  :|||         |:|    |.||..||       ||.:|||
 Worm   489 TTTTTEKPVITEGSTTNKQPTT---------SEH----ESTTEVPT-------TTEEPTT----- 528

  Fly  1238 GTTAKSTTLKPTEGTSAKPTTLKPTEGTTAKPTTLKPTEGTSAKPTTLKPTEGTTAKPTTLKPTE 1302
             ||.:..|.|..  |:.:|||.:.: .||.:.||.:....|...|||..||  ||.:||
 Worm   529 -TTGQHKTEKAI--TTEEPTTTEES-STTEEVTTTEEPANTGNPPTTENPT--TTEQPT------ 581

  Fly  1303 GTTAKPTTLKPTEGTSAKPTTLKPTEGTTAKPTTLKPTEGTSAKPTTLKPTEGTTAKPTTLKPTE 1367
             :||:.|       |:|.|.|.:.|. ||.:|||.:.:..|. ||||.:.:..|....||.|.:
 Worm   582 -STAEST-------TTALPFTTEQTV-TTEEPTTAEKSTATQ-KPTTTQESVSTEKTSTTKKAS- 635

  Fly  1368 GTTAKPTTLKPTEGTTAKPTTLKPTE-GTSAKPTTLKPTEGTTAKPTTLNAKPTTLK-PTEGTTA 1430
             ||.:||       ||.:|||  .|| .|:.|.||  |...||::.||    .|.|| .|||:|
 Worm   636 -TTEEPT-------TTDEPTT--TTESSTTGKATT--PELSTTSEETT----TTELKITTEGST- 683

  Fly  1431 KPTTLKPTEGTSAKPTTLKPTEGTTAKPTTLKPTEGTTAQPTTLKPTEGTTAKPTTLKP--TEGT 1493
              ||.:||       ||....|.:|...||.:.|..||:          ||.:.|:.|.  ||..
 Worm   684 --TTEEPT-------TTAIFAEASTGIITTDEETTSTTS----------TTPEITSTKEIVTESA 729

  Fly  1494 SAQPTTLKPTEGTTAK--PTTLKP--------TEGTSAKPTTLKPTEGTTAKPTTLKPTEGTSAQ 1548
            ..| |::...|.:|.:  |...|.        .|....|...||..|.|:        |.|:.:.
 Worm   730 ITQ-TSVSVVESSTPRQLPERWKAIVNKFKHNLEVLKEKKRLLKEKESTS--------TTGSDSS 785

  Fly  1549 PTTLKPTEGTSAQSTT-----LKPTEGTTAKPTTLKPTEGTSAKPTTLKPTEGTTAKPTTLKPTE 1608
            .||....|.....:||     ::.|..||.|.||.:.|      .||...||.||:|.||.|||.
 Worm   786 ETTTVVAENIDEVTTTEKEKVVQTTPITTEKSTTQEET------TTTTTTTEKTTSKTTTEKPTT 844

  Fly  1609 GTSAKPTTLKPTEGTTAKPTTLKPTEGTTAKPTTLKPTEGTSAKPTTLKPTEGTSAKPTTLKPTE 1673
            ..||      .||.||::|:|   ||.||...::....|.::|..||.     |||:  |.:.|.
 Worm   845 SESA------TTETTTSEPST---TESTTVDTSSATTEESSTAAETTT-----TSAE--TSETTT 893

  Fly  1674 GTSAKPTTLKPTEGTSAQPTTLKPTEGTSA--KP------------TTLKPTEGTT---AKPTTL 1721
            ..||...|.:..|.|:.|.::.|..|..|:  ||            ||:||.|.|:   |..||.
 Worm   894 SESAAFITGESPENTALQSSSQKSEENESSAEKPGARRDFVPKKHKTTVKPAETTSAVAASTTTT 958

  Fly  1722 KPTDGTTAKPTTLKPTEGTSAKPTTLKPTEG---TTAKP---TTLKPTEGTSAKPTTLKPTEGTT 1780
            :|.. ||.|.|||   |.|..:.|||....|   .|..|   ||:...|..|    .:..|:.:.
 Worm   959 EPIT-TTEKSTTL---ETTPIEATTLNEVTGPAFVTGAPVDETTINTLELLS----KINNTQISQ 1015

  Fly  1781 AKPTTLKPTEGTSA---------QPTTLKPTERTSAQPTTLKPTEGTTAKPTTLKPTEGTSAQPT 1836
            .|||.:..|:..|:         ....:.||..|:.....:..||.:....:..|..:  .||||
 Worm  1016 PKPTDISKTDALSSLISGLIGSFTKAPMAPTIHTTTDAAFVTATEASLNDGSDKKIID--EAQPT 1078

  Fly  1837 TLKPTEGTTAKPT 1849
                .|...|:||
 Worm  1079 ----DEIRRAQPT 1087

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Muc12Ea	NP_001368944.1	PHA03247	<175..670	CDD:223021
		PHA03247	<659..1197	CDD:223021	155/478 (32%)
		PHA03247	<1049..1651	CDD:223021	206/634 (32%)
		PHA03247	<1723..2186	CDD:223021	39/142 (27%)
		PHA03247	<2110..2706	CDD:223021
dpy-6	NP_509435.2	GBP_C	<1089..1182	CDD:303769
		coiled coil	1157..1166	CDD:293879

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000