DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1461 and alaC

DIOPT Version :9

Sequence 1:	NP_001285238.1	Gene:	CG1461 / 32381	FlyBaseID:	FBgn0030558	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_416880.1	Gene:	alaC / 946850	ECOCYCID:	G7242	Length:	412	Species:	Escherichia coli

Alignment Length:	411	Identity:	94/411 - (22%)
Similarity:	165/411 - (40%)	Gaps:	103/411 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 NIVESLKIKPNPE-KPMIPLSIGDPTTFGNLKAADETMKAVLHSL----ESGKYNGYASTQGHEI 155
            ||...||:..... :.:|..|:|:|.        ..|...::..|    :....:||::::|...
E. coli    22 NITAELKMAARRRGEDIIDFSMGNPD--------GATPPHIVEKLCTVAQRPDTHGYSTSRGIPR 78

  Fly   156 ARKAVAKYSAHQRPDGEID-ANEVVLCSGCSSALEYCILALADRGQNVLVPRPGFCLYYTLAQGL 219
            .|:|:::: ...|.|.||| .:|.::..|....|.:.:||..|.|..||||.|.:.::...|...
E. coli    79 LRRAISRW-YQDRYDVEIDPESEAIVTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIA 142

  Fly   220 DIEVRYYDLLPDQQWRADLVQLESLIDEN---TAALLINNPSNPCGSVFDEKHLRELIAICERHY 281
            ..:||...|:....:   ..:||..|.|:   ...:::..||||.....:.:...:::|:.:|:.
E. coli   143 GAQVRSVPLVEGVDF---FNELERAIRESYPKPKMMILGFPSNPTAQCVELEFFEKVVALAKRYD 204

  Fly   282 LPIIADEIYEHFVF-----------PGSKHLAVSSLTTEVPVLSCGGLTKRFLVPGWRMGWIIVH 335
            :.::.|..|...|:           ||::.:||...|          |:|.:.:.|||:|:::
E. coli   205 VLVVHDLAYADIVYDGWKAPSIMQVPGARDVAVEFFT----------LSKSYNMAGWRIGFMV-- 257

  Fly   336 DRKNRLRDAIVGLKNMCGRILGSNTIIQGALPDILTKTPQSYFD-GVIDVLHSNAMLA------- 392
                                 |:.|:: .||..|     :||.| |....|...|:.|
E. coli   258 ---------------------GNKTLV-SALARI-----KSYHDYGTFTPLQVAAIAALEGDQQC 295

  Fly   393 -------YKMLKQ--VRGLDPV-----MPNGAMYMMIGVSIERFPE---FKDDTHFVQEMVNEQS 440
                   ||..:.  |:||...     ||..:||:.     .:.||   ......|.::::||..
E. coli   296 VRDIAEQYKRRRDVLVKGLHEAGWMVEMPKASMYVW-----AKIPEPYAAMGSLEFAKKLLNEAK 355

  Fly   441 VFCLPGSCFEYPG--YVRIVL 459
            |...||..|...|  :||..|
E. coli   356 VCVSPGIGFGDYGDTHVRFAL 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1461	NP_001285238.1	tyr_amTase_E	79..481	CDD:273529	94/411 (23%)
CG1461	NP_001285238.1	AAT_like	112..475	CDD:99734	90/394 (23%)
alaC	NP_416880.1	PRK08175	8..402	CDD:181268	94/411 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0436
Hieranoid	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1408
SwiftOrtho	0	0.000	Not matched by this tool.
	3	2.810