DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1461 and BNA3

DIOPT Version :9

Sequence 1:	NP_001285238.1	Gene:	CG1461 / 32381	FlyBaseID:	FBgn0030558	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_012475.3	Gene:	BNA3 / 853386	SGDID:	S000003596	Length:	444	Species:	Saccharomyces cerevisiae

Alignment Length:	483	Identity:	118/483 - (24%)
Similarity:	187/483 - (38%)	Gaps:	95/483 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 KQQDLVDTTATSSSSRKRSGWEIKGSKLSLNTHNRIRNIVESLKIK-----PNPEKPMIPLSIG- 117
            ||:.:...|...|:||.:   .:.....:.||...:.::......|     .|..:.:|.|..|
Yeast     2 KQRFIRQFTNLMSTSRPK---VVANKYFTSNTAKDVWSLTNEAAAKAANNSKNQGRELINLGQGF 63

  Fly   118 ---DPTTFGNLKAADETMKAVLHSLESGKYNGYASTQGH-EIARKAVAKYSAHQRP--DGEIDAN 176
               .|..|    |..|..||    |:....|.|:.|:|. .:....:..||    |  :.|:.|.
Yeast    64 FSYSPPQF----AIKEAQKA----LDIPMVNQYSPTRGRPSLINSLIKLYS----PIYNTELKAE 116

  Fly   177 EVVLCSGCSSALEYCILALADRGQNVLVPRPGFCLYYTLAQGLDIEVRYYDLLP----DQ----- 232
            .|.:.:|.:..:..|::.|.:.|..|:|..|.|..|....:....:|.|..:.|    ||
Yeast   117 NVTVTTGANEGILSCLMGLLNAGDEVIVFEPFFDQYIPNIELCGGKVVYVPINPPKELDQRNTRG 181

  Fly   233 -QWRADLVQLESLIDENTAALLINNPSNPCGSVFDEKHLRELIAICERHYLPIIADEIYEHFVFP 296
             :|..|..|.|..|...|.|::||.|.||.|.||..:.|..|..||.:|.:.||:||:|||..|.
Yeast   182 EEWTIDFEQFEKAITSKTKAVIINTPHNPIGKVFTREELTTLGNICVKHNVVIISDEVYEHLYFT 246

  Fly   297 GSKHLAVSSLTTEVP--VLSCGGLTKRFLVPGWRMGWI-------IVHDRKNRLRDAIVG---LK 349
            .| ...:::|:.|:.  .|:.|...|.|...|||:||:       :.:..|...|.....   |:
Yeast   247 DS-FTRIATLSPEIGQLTLTVGSAGKSFAATGWRIGWVLSLNAELLSYAAKAHTRICFASPSPLQ 310

  Fly   350 NMCGRILGSNTIIQGALPDILTKTPQSY------FDGVIDVLHSNAMLAYKMLKQVRGLDPVMPN 408
            ..|     :|:|..........|..|.|      |..:.|.|               ||....|.
Yeast   311 EAC-----ANSINDALKIGYFEKMRQEYINKFKIFTSIFDEL---------------GLPYTAPE 355

  Fly   409 GAMYMMIGVSIERFPEFKDDTHFVQEMVNEQSVFCLPGSCFEYPGYVRIVLTVPGAMIEEACSRI 473
            |..::::..|..:.||   |..:.:|::|:...|.:........|.|.|..|
Yeast   356 GTYFVLVDFSKVKIPE---DYPYPEEILNKGKDFRISHWLINELGVVAIPPT------------- 404

  Fly   474 AEFCDRHYKKESRNFIEHGLLDCDDVAF 501
             ||..:.::|.:.|.:...:  |.|.|:
Yeast   405 -EFYIKEHEKAAENLLRFAV--CKDDAY 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1461	NP_001285238.1	tyr_amTase_E	79..481	CDD:273529	107/441 (24%)
CG1461	NP_001285238.1	AAT_like	112..475	CDD:99734	101/397 (25%)
BNA3	NP_012475.3	AspB	54..444	CDD:223513	108/428 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0436
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810