Protein Alignment Tat and ALT2

DIOPT Version :10

• Sequence 1: NP_572953.1
• Gene: Tat / 32381
• FlyBaseID: FBgn0030558
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_010396.1
• Gene: ALT2 / 851690
• SGDID: S000002518
• Length: 507
• Species: Saccharomyces cerevisiae
• Alignment Length: 501
• Identity: 118/501 - (23%)
• Similarity: 201/501 - (40%)
• Gaps: 116/501 - (23%)

  Fly    60 QQDLVDTTATSSSSRKRSGWEIKGSKLSLNT---------HNRIRNIVESLK--IKPNPE----K 109
            ||||...........|.:|   |.:|..|||         ...|....:.||  :|.|||    .
Yeast     6 QQDLKGVFTAKDLDFKPAG---KITKKDLNTGVTKAEYAVRGAIPTRADELKEELKKNPEVLPFD 67

  Fly   110 PMIPLSIGD-------PTTFG-----------------------NLKAAD--ETMKAVLHSLESG 142
            .:|..:||:       |.||.                       ||.:.|  |..:.:|:.: .|
Yeast    68 DIINANIGNPQQLDQKPLTFTRQVLAILEYPEILRVGHNELASLNLFSRDALERAERLLNDI-GG 131

  Fly   143 KYNGYASTQGHEIARKAVAKYSAHQRPDGE-IDANEVVLCSGCSSALEYCI-LALADRGQNVLVP 205
            ....|:.:||....|:.||.:.. :|..|| ....::.|.:|.|||....: |...|....:|:|
Yeast   132 SIGAYSHSQGVPGIRQTVADFIT-RRDGGEPATPEDIYLTTGASSAATSLLSLLCKDSQTGLLIP 195

  Fly   206 RPGFCLYYTLAQGLDIEVRYYDLLPDQQWRADLVQLESLIDE------NTAALLINNPSNPCGSV 264
            .|.:.||...|...:.:|..|.|..:..|..:..::|.::.:      ..:.|::.||.||.|:|
Yeast   196 IPQYPLYTASASLFNAQVLPYYLDEESNWSTNSDEIEKVVQDALKKQIRPSVLIVINPGNPTGAV 260

  Fly   265 FDEKHLRELIAICERHYLPIIADEIYEHFVFPGSKHLAVSSLTTE-----------VPVLSCGGL 318
            ..|:.:..:..|..::.:.||:||:|:..:|...|..::..:..:           |.:.|...:
Yeast   261 LSEETIARICLIAAKYGITIISDEVYQENIFNDVKFHSMKKVLRKLQHLYPGKFDNVQLASLHSI 325

  Fly   319 TKRFLVP-GWRMGWIIVHDRKNRLRDAIVGLK--NMCGRILGSNTIIQGALPDILTKTPQ----S 376
            :|.|:.. |.|.|::.:......:|||:..|.  ::|..:.|.      |:.|::.|.||    |
Yeast   326 SKGFMDECGQRGGYMEIIGFSQEIRDALFKLMSISICSVVTGQ------AVVDLMVKPPQPGDES 384

  Fly   377 Y---FDGVIDVLH---SNAMLAYKMLKQVRGLDPVMPNGAMYMMIGVSIERFPE----------- 424
            |   .|..:.:.|   :.|.|.|:..|::.|::...|.||||:        ||.
Yeast   385 YEQDHDERLKIFHEMRTRANLLYETFKELEGIECQKPQGAMYL--------FPRLVLPKKALCES 441

  Fly   425 ----FKDDTHFVQEMVNEQSVFCLPGSCF-EYPG--YVRIVLTVPG 463
                .:.|..:...::....:..:|||.| :.||  :||.....||
Yeast   442 ERLGIEPDEFYCTSLLESTGICTVPGSGFGQRPGTYHVRTTFLAPG 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tat	NP_572953.1	tyr_amTase_E	79..481	CDD:273529	112/482 (23%)
ALT2	NP_010396.1	PTZ00377	26..505	CDD:240391	111/478 (23%)