DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1461 and ALT2

DIOPT Version :9

Sequence 1:	NP_001285238.1	Gene:	CG1461 / 32381	FlyBaseID:	FBgn0030558	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_010396.1	Gene:	ALT2 / 851690	SGDID:	S000002518	Length:	507	Species:	Saccharomyces cerevisiae

Alignment Length:	501	Identity:	118/501 - (23%)
Similarity:	201/501 - (40%)	Gaps:	116/501 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 QQDLVDTTATSSSSRKRSGWEIKGSKLSLNT---------HNRIRNIVESLK--IKPNPE----K 109
            ||||...........|.:|   |.:|..|||         ...|....:.||  :|.|||    .
Yeast     6 QQDLKGVFTAKDLDFKPAG---KITKKDLNTGVTKAEYAVRGAIPTRADELKEELKKNPEVLPFD 67

  Fly   110 PMIPLSIGD-------PTTFG-----------------------NLKAAD--ETMKAVLHSLESG 142
            .:|..:||:       |.||.                       ||.:.|  |..:.:|:.: .|
Yeast    68 DIINANIGNPQQLDQKPLTFTRQVLAILEYPEILRVGHNELASLNLFSRDALERAERLLNDI-GG 131

  Fly   143 KYNGYASTQGHEIARKAVAKYSAHQRPDGE-IDANEVVLCSGCSSALEYCI-LALADRGQNVLVP 205
            ....|:.:||....|:.||.:.. :|..|| ....::.|.:|.|||....: |...|....:|:|
Yeast   132 SIGAYSHSQGVPGIRQTVADFIT-RRDGGEPATPEDIYLTTGASSAATSLLSLLCKDSQTGLLIP 195

  Fly   206 RPGFCLYYTLAQGLDIEVRYYDLLPDQQWRADLVQLESLIDE------NTAALLINNPSNPCGSV 264
            .|.:.||...|...:.:|..|.|..:..|..:..::|.::.:      ..:.|::.||.||.|:|
Yeast   196 IPQYPLYTASASLFNAQVLPYYLDEESNWSTNSDEIEKVVQDALKKQIRPSVLIVINPGNPTGAV 260

  Fly   265 FDEKHLRELIAICERHYLPIIADEIYEHFVFPGSKHLAVSSLTTE-----------VPVLSCGGL 318
            ..|:.:..:..|..::.:.||:||:|:..:|...|..::..:..:           |.:.|...:
Yeast   261 LSEETIARICLIAAKYGITIISDEVYQENIFNDVKFHSMKKVLRKLQHLYPGKFDNVQLASLHSI 325

  Fly   319 TKRFLVP-GWRMGWIIVHDRKNRLRDAIVGLK--NMCGRILGSNTIIQGALPDILTKTPQ----S 376
            :|.|:.. |.|.|::.:......:|||:..|.  ::|..:.|.      |:.|::.|.||    |
Yeast   326 SKGFMDECGQRGGYMEIIGFSQEIRDALFKLMSISICSVVTGQ------AVVDLMVKPPQPGDES 384

  Fly   377 Y---FDGVIDVLH---SNAMLAYKMLKQVRGLDPVMPNGAMYMMIGVSIERFPE----------- 424
            |   .|..:.:.|   :.|.|.|:..|::.|::...|.||||:        ||.
Yeast   385 YEQDHDERLKIFHEMRTRANLLYETFKELEGIECQKPQGAMYL--------FPRLVLPKKALCES 441

  Fly   425 ----FKDDTHFVQEMVNEQSVFCLPGSCF-EYPG--YVRIVLTVPG 463
                .:.|..:...::....:..:|||.| :.||  :||.....||
Yeast   442 ERLGIEPDEFYCTSLLESTGICTVPGSGFGQRPGTYHVRTTFLAPG 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1461	NP_001285238.1	tyr_amTase_E	79..481	CDD:273529	112/482 (23%)
CG1461	NP_001285238.1	AAT_like	112..475	CDD:99734	100/434 (23%)
ALT2	NP_010396.1	PTZ00377	26..505	CDD:240391	111/478 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0436
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810