Protein Alignment CG1461 and GPT2

DIOPT Version :9

• Sequence 1: NP_001285238.1
• Gene: CG1461 / 32381
• FlyBaseID: FBgn0030558
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_597700.1
• Gene: GPT2 / 84706
• HGNCID: 18062
• Length: 523
• Species: Homo sapiens
• Alignment Length: 549
• Identity: 122/549 - (22%)
• Similarity: 220/549 - (40%)
• Gaps: 114/549 - (20%)

  Fly    19 RASCTSRSPS---EPESPAPVTPNCDVVDQALAELQLQSQDIRKQQDLVDTTATSSSSRKRSGWE 80
            |..|..|:||   ..:|.|..        :|.|.|:::.:..|:::.|  |..:.:...|...:.
Human     9 RRGCGPRTPSSWGRSQSSAAA--------EASAVLKVRPERSRRERIL--TLESMNPQVKAVEYA 63

  Fly    81 IKG------SKLSLNTHNRIRNIVESLKIKPNPEKPMIPLSIGD-------PTTF---------- 122
            ::|      .::.|.....|:        ||..|  :|..:|||       |.||
Human    64 VRGPIVLKAGEIELELQRGIK--------KPFTE--VIRANIGDAQAMGQQPITFLRQVMALCTY 118

  Fly   123 GNL-------KAADETMKAVLHSLESGKYNGYASTQGHEIARKAVAKYSAHQRPDGEI--DANEV 178
            .||       :.|.:..:.:|.:........|:::||....|:.||.|..  |.||.:  |.:.:
Human   119 PNLLDSPSFPEDAKKRARRILQACGGNSLGSYSASQGVNCIREDVAAYIT--RRDGGVPADPDNI 181

  Fly   179 VLCSGCSSALEYCILALADRG----QNVLVPRPGFCLYYTLAQGLD-IEVRYYDLLPDQQWRADL 238
            .|.:|.|..:...:..|...|    ..|::|.|.:.||..:...|| |:|.|| |..:..|..::
Human   182 YLTTGASDGISTILKILVSGGGKSRTGVMIPIPQYPLYSAVISELDAIQVNYY-LDEENCWALNV 245

  Fly   239 VQLESLIDE-----NTAALLINNPSNPCGSVFDEKHLRELIAICERHYLPIIADEIYEHFVF-PG 297
            .:|...:.|     :...|.|.||.||.|.|...|.:.::|.......|.::|||:|:..|: |.
Human   246 NELRRAVQEAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADEVYQDNVYSPD 310

  Fly   298 SKHLAVSSL--------TTEVPVLSCGGLTKRFLVP-GWRMGWIIVHDRKNRLRDAIVGLKN--M 351
            .:..:...:        ::.|.:.|....:|.::.. |:|.|::.|.:....::..:|.|.:  :
Human   311 CRFHSFKKVLYEMGPEYSSNVELASFHSTSKGYMGECGYRGGYMEVINLHPEIKGQLVKLLSVRL 375

  Fly   352 CGRILGSNTIIQGALPDILTKTP----QSY------FDGVIDVLHSNAMLAYKMLKQVRGLDPVM 406
            |..:.|     |.|: ||:...|    :|:      .:.|:..|...|.|...:..||.|:....
Human   376 CPPVSG-----QAAM-DIVVNPPVAGEESFEQFSREKESVLGNLAKKAKLTEDLFNQVPGIHCNP 434

  Fly   407 PNGAMYMM-------IGVSIERFPEFKDDTHFVQEMVNEQSVFCLPGSCF---EYPGYVRIVLTV 461
            ..||||..       ..|...:..:...|..:..:::.|..:..:|||.|   |...:.|:.:..
Human   435 LQGAMYAFPRIFIPAKAVEAAQAHQMAPDMFYCMKLLEETGICVVPGSGFGQREGTYHFRMTILP 499

  Fly   462 PGAMIEEACSRIAEFCDRHYKKESRNFIE 490
            |...::....::.:|   |.     ||:|
Human   500 PVEKLKTVLQKVKDF---HI-----NFLE 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1461	NP_001285238.1	tyr_amTase_E	79..481	CDD:273529	104/475 (22%)
		AAT_like	112..475	CDD:99734	97/430 (23%)
GPT2	NP_597700.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25		5/15 (33%)
		PTZ00377	48..523	CDD:240391	111/502 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0436
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810