DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1461 and ACS12

DIOPT Version :9

Sequence 1:	NP_001285238.1	Gene:	CG1461 / 32381	FlyBaseID:	FBgn0030558	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_199982.2	Gene:	ACS12 / 835243	AraportID:	AT5G51690	Length:	495	Species:	Arabidopsis thaliana

Alignment Length:	534	Identity:	103/534 - (19%)
Similarity:	209/534 - (39%)	Gaps:	149/534 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPSSFANESQFRYQSSRNRASCTSRSPSEPESPAPVTPNCDVVDQALAELQLQSQDIRKQQDLVD 65
            :|.:|:..:.|...:|..|...:||:       .||....|
plant    48 LPRTFSRTNLFSRGNSIGRVRVSSRA-------VPVAKPSD------------------------ 81

  Fly    66 TTATSSSSRKRSGWEIKGSKLSLNTHNRIRNIVESLKIKPNPEKPMIPLSIGDPTTFGNLK---A 127
                       |.:.|...::..:.::||.|           ...:|.|.:.:.|...:|.   .
plant    82 -----------SPYYIGLERVKTDPYDRITN-----------TDGIIQLGLAESTLCFDLLQRWM 124

  Fly   128 ADETMKAVLHSLESGKYN-----GYASTQGHEIARKAVAKY-SAHQRPDGEIDANEVVLCSGCSS 186
            ::..|::::.| :.|:::     .|...:|....|.|.|.: |.....:...|.:.:|:.:|.:.
plant   125 SENLMESMMQS-DDGEFDISSIAMYKPFEGLLELRVAFADFMSRIMGGNVSFDPSNMVITAGGTP 188

  Fly   187 ALEYCILALADRGQNVLVPRPGFCLYYTLAQGLDIEVRY---YDLLP-----DQQWRADLVQLES 243
            |:|.....|||.|...|:|.|    ||   .|.|.::::   .:|:|     ...:...:..||.
plant   189 AIEVLAFCLADHGNAFLIPTP----YY---PGFDRDIKFRTGVELIPVHCRSSDNFTVTVSALEQ 246

  Fly   244 LIDE------NTAALLINNPSNPCGSVFDEKHLRELIAICERHYLPIIADEIYEHFVFPGSKHLA 302
            .:::      ..:.:|.:|||||.|::...:.|.:::...:...:.:|:|||:...|:...:.::
plant   247 ALNQARKRGSKVSGILFSNPSNPVGNILSRETLCDILRFAQEKNIHVISDEIFAGSVYGDKEFVS 311

  Fly   303 VSSLT-------TEVPVLSCGGLTKRFLVPGWRMGWI------IVHDRKNRLRDAIVGLKNMCGR 354
            ::.:.       |.|.::.  ||:|...:||:|.|.|      :|:..|..:|.:.|.:
plant   312 MAEIAGSGEFDKTRVHIIY--GLSKDLSIPGFRAGVIYSFHEDVVNAAKKLMRFSSVPV------ 368

  Fly   355 ILGSNTIIQGALPDILTKTPQSYFDGVIDVLHSNAMLAYKM------------LKQVRGLDPVMP 407
                  ::|..|..:|:..  .:.:|.        |.|::.            |||: |:.....
plant   369 ------LVQRILISLLSDV--RFIEGY--------MAAHRQRIRDKHIRFVEGLKQL-GIPCAES 416

  Fly   408 NGAMYMMIGVS--IERFPEFKDDTHFVQEMVNEQSVFCLPGS---CFEYPGYVRIVLT------V 461
            .|.:|..:.:|  :..:.| |.:....::::....:...||:   |.| ||:.|...|      :
plant   417 GGGLYCWVDMSSLLTSYSE-KGELELFEKLLTVAKINATPGTACYCIE-PGWFRCCFTALADEDI 479

  Fly   462 PGAMIEEACSRIAE 475
            |  :|.|...::||
plant   480 P--VIMERIRQLAE 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1461	NP_001285238.1	tyr_amTase_E	79..481	CDD:273529	92/456 (20%)
CG1461	NP_001285238.1	AAT_like	112..475	CDD:99734	86/421 (20%)
ACS12	NP_199982.2	PLN02450	70..495	CDD:178069	98/512 (19%)
		AAT_I	81..213	CDD:302748	33/185 (18%)
		AAT_like	148..488	CDD:99734	79/375 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0436
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810