DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1461 and ACS1

DIOPT Version :9

Sequence 1:	NP_001285238.1	Gene:	CG1461 / 32381	FlyBaseID:	FBgn0030558	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_191710.1	Gene:	ACS1 / 825324	AraportID:	AT3G61510	Length:	488	Species:	Arabidopsis thaliana

Alignment Length:	498	Identity:	106/498 - (21%)
Similarity:	184/498 - (36%)	Gaps:	129/498 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 QQDLVDTTATSSSSRKRS----GWEIKGSKLSLNTHNRIRNIVES-----------LK--IKPNP 107
            :..|:...|.|....:.|    ||:...:.....|||. :.:::.           :|  ||.||
plant     7 ENQLLSKLALSDKHGEASPYFHGWKAYDNNPFHPTHNP-QGVIQMGLAENQLCSDLIKEWIKENP 70

  Fly   108 EKPMIPLSIGDPTTFGNLKAADETMKAVLHSLESGKYNGYASTQGHEIARKAVAKYSAHQRPDGE 172
            :..:.       |..|....:|..:....|.|:.              .|:|:|.:....| .|.
plant    71 QASIC-------TAEGIDSFSDIAVFQDYHGLKQ--------------FRQAIATFMERAR-GGR 113

  Fly   173 I--DANEVVLCSGCSSALEYCILALADRGQNVLVPRPGFCLYYTLAQGLDIEVRYYDLLPDQQWR 235
            :  :|..||:..|.:.|.|..:..|||.|...|||.|    ||..          :|  .|.:||
plant   114 VRFEAERVVMSGGATGANETIMFCLADPGDAFLVPTP----YYAA----------FD--RDLRWR 162

  Fly   236 AD--LVQLESLIDEN---------------------TAALLINNPSNPCGSVFDEKHLRELIAIC 277
            ..  ::.:|.....|                     ...|:|   |||.|:..|.:.|..|::..
plant   163 TGVRIIPVECSSSNNFQITKQALESAYLKAQETGIKIKGLII---SNPLGTSLDRETLESLVSFI 224

  Fly   278 ERHYLPIIADEIYEHFVFPGSKHLAVSSLTTEVPVLS------CGGLTKRFLVPGWRMGWIIVHD 336
            ....:.::.||||...||.....::|:.:..|:..::      ...|:|...:||:|:|.:..::
plant   225 NDKQIHLVCDEIYAATVFAEPGFISVAEIIQEMYYVNRDLIHIVYSLSKDMGLPGFRVGVVYSYN 289

  Fly   337 RKNRLRDAIVGLKNMCGRILGSNTIIQGALPDILTK--TPQSYFDGVIDVLHSNAMLAYKMLK-- 397
                  |.:|.    |.|.:.|..::.......|..  :.||:.|..:..:.......:.|..
plant   290 ------DVVVS----CARRMSSFGLVSSQTQSFLAAMLSDQSFVDNFLVEVSKRVAKRHHMFTEG 344

  Fly   398 -QVRGLDPVMPNGAMYMMIGVSIERFPEFKDDTHFVQEM------VNEQSVFCLPGSCF--EYPG 453
             :..|:..:..|..:::::.:.    ...||.| |..||      :|:..:...|||.|  ..||
plant   345 LEEMGISCLRSNAGLFVLMDLR----HMLKDQT-FDSEMALWRVIINKVKINVSPGSSFHCSEPG 404

  Fly   454 YVRIVLTVPGAMIEE-----ACSRIAEFC--DRHYKKESRNFI 489
            :.|:..    |.::|     |..||.:|.  ||..|.::.|.|
plant   405 WFRVCF----ANMDEDTLQIALERIKDFVVGDRANKNKNCNCI 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1461	NP_001285238.1	tyr_amTase_E	79..481	CDD:273529	98/465 (21%)
CG1461	NP_001285238.1	AAT_like	112..475	CDD:99734	86/411 (21%)
ACS1	NP_191710.1	PLN02994	3..154	CDD:166635	40/173 (23%)
		PLN02376	4..488	CDD:178004	106/498 (21%)
		AAT_like	89..427	CDD:99734	83/390 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0436
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810