DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1461 and Gpt

DIOPT Version :9

Sequence 1:	NP_001285238.1	Gene:	CG1461 / 32381	FlyBaseID:	FBgn0030558	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_112301.1	Gene:	Gpt / 81670	RGDID:	621720	Length:	496	Species:	Rattus norvegicus

Alignment Length:	492	Identity:	112/492 - (22%)
Similarity:	207/492 - (42%)	Gaps:	100/492 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 SSRKRSGWEIKGSKLSLNTHNR-IRNIVESLK-------------IKPNPEKP---MIPLSIGD- 118
            |...|:|  :||..|:|:|.|. :|.:..:::             ::...:||   :|..:|||
  Rat     9 SQASRNG--LKGKVLTLDTMNPCVRRVEYAVRGPIVQRALELEQELRQGVKKPFTEVIRANIGDA 71

  Fly   119 ------PTTF----------GNL-------KAADETMKAVLHSLESGKYNGYASTQGHEIARKAV 160
                  |.||          .||       :.|....:.:|.:........|:.:.|.:..|:.|
  Rat    72 QAMGQRPITFFRQVLALCVYPNLLSSPDFPEDAKRRAERILQACGGHSLGAYSISSGIQPIREDV 136

  Fly   161 AKYSAHQRPDGEI--DANEVVLCSGCSSALEYCI-LALADRGQ---NVLVPRPGFCLYYTLAQGL 219
            |:|.  :|.||.|  |.|.:.|.:|.|.|:...: |.::..|:   .||:|.|.:.||......|
  Rat   137 AQYI--ERRDGGIPADPNNIFLSTGASDAIVTMLKLLVSGEGRARTGVLIPIPQYPLYSAALAEL 199

  Fly   220 D-IEVRYYDLLPDQQWRADLVQLESLIDEN-----TAALLINNPSNPCGSVFDEKHLRELIAICE 278
            | ::|.|| |..::.|..|:.:|...:.:.     ...|.:.||.||.|.|...:.:..:|....
  Rat   200 DAVQVDYY-LDEERAWALDIAELRRALCQARDRCCPRVLCVINPGNPTGQVQTRECIEAVIRFAF 263

  Fly   279 RHYLPIIADEIYEHFVF-PGSKHLAVSSL--------TTEVPVLSCGGLTKRFLVP-GWRMGWII 333
            :..|.::|||:|:..|: .||:..:...:        :|:..:.|...::|.::.. |:|.|::.
  Rat   264 KEGLFLMADEVYQDNVYAEGSQFHSFKKVLMEMGPPYSTQQELASFHSVSKGYMGECGFRGGYVE 328

  Fly   334 VHDRKNRLRDAIVGLKN--MCGRILGSNTIIQGALPDILTKTP----------QSYFDGVIDVLH 386
            |.:....::..:..|.:  :|..:.|.      ||.|::...|          |:....|:..|.
  Rat   329 VVNMDAEVQKQMGKLMSVRLCPPVPGQ------ALMDMVVSPPTPSEPSFKQFQAERQEVLAELA 387

  Fly   387 SNAMLAYKMLKQVRGL--DPVMPNGAMYMMIGV-----SIERFPE--FKDDTHFVQEMVNEQSVF 442
            :.|.|..::..:..|:  :||  .||||....|     :::|..|  ...|..|...::.|..:.
  Rat   388 AKAKLTEQVFNEAPGIRCNPV--QGAMYSFPQVQLPLKAVQRAQELGLAPDMFFCLCLLEETGIC 450

  Fly   443 CLPGSCF---EYPGYVRIVLTVPGAMIEEACSRIAEF 476
            .:|||.|   |...:.|:.:..|...:.....:::.|
  Rat   451 VVPGSGFGQQEGTYHFRMTILPPMEKLRLLLEKLSHF 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1461	NP_001285238.1	tyr_amTase_E	79..481	CDD:273529	109/485 (22%)
CG1461	NP_001285238.1	AAT_like	112..475	CDD:99734	99/432 (23%)
Gpt	NP_112301.1	PTZ00377	19..496	CDD:240391	107/480 (22%)
Gpt	NP_112301.1	AAT_like	98..473	CDD:99734	89/385 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0436
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810