DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1461 and SUR1

DIOPT Version :9

Sequence 1:	NP_001285238.1	Gene:	CG1461 / 32381	FlyBaseID:	FBgn0030558	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_179650.1	Gene:	SUR1 / 816585	AraportID:	AT2G20610	Length:	462	Species:	Arabidopsis thaliana

Alignment Length:	445	Identity:	137/445 - (30%)
Similarity:	229/445 - (51%)	Gaps:	11/445 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 DQALAELQLQSQDIRKQQDLVDTTATSSSSRKRSGWEIKGSKLSLNTHNRIRNIVESL--KIKPN 106
            :|..|.|.:.:  .:.:::.:..|....||..|.|...|.:|.|..|   :|.::..|  ....:
plant     4 EQPHANLAVPA--FKTEKEPITQTRNGQSSVWRFGGSDKAAKASTVT---LRGVIYMLFDNCGKD 63

  Fly   107 PEKPMIPLSIGDPTTFGNLKAADETMKAVLHSLESGKYNGYASTQGHEIARKAVAKYSAHQRPDG 171
            ..|.::||..|||:.:...:...|...||:..|.|||.|.|....|...||:|||.|.....|.
plant    64 VNKTILPLGHGDPSVYPCFRTCIEAEDAVVDVLRSGKGNSYGPGAGILPARRAVADYMNRDLPH- 127

  Fly   172 EIDANEVVLCSGCSSALEYCILALADRGQNVLVPRPGFCLYYTLAQGLDIEVRYYDLLPDQQWRA 236
            ::...::.|.:||:..:|....:||....|:|:|||||..|...|....:|||.:||||:::|..
plant   128 KLTPEDIFLTAGCNQGIEIVFESLARPNANILLPRPGFPHYDARAAYSGLEVRKFDLLPEKEWEI 192

  Fly   237 DLVQLESLIDENTAALLINNPSNPCGSVFDEKHLRELIAICERHYLPIIADEIYEHFVFPGSKHL 301
            ||..:|::.||||.|:::.||:||||:|:...||:::.....:..:.:|:||:|:..:|..:..:
plant   193 DLEGIEAIADENTVAMVVINPNNPCGNVYSHDHLKKVAETARKLGIMVISDEVYDRTIFGDNPFV 257

  Fly   302 AVSSLTTEVPVLSCGGLTKRFLVPGWRMGWIIVHDRKN--RLRDAIVGLKNMCGRILGSNTIIQG 364
            ::....:.||||:..|::|.::||||::|||.::|.:.  .....:..:|..........||||.
plant   258 SMGKFASIVPVLTLAGISKGWVVPGWKIGWIALNDPEGVFETTKVLQSIKQNLDVTPDPATIIQA 322

  Fly   365 ALPDILTKTPQSYFDGVIDVLHSNAMLAYKMLKQVR-GLDPVMPNGAMYMMIGVSIERFPEFKDD 428
            |||.||.|..:::|.....:|..|..|....||.:. .:.|..|....|::..:.:......|||
plant   323 ALPAILEKADKNFFAKKNKILKHNVDLVCDRLKDIPCVVCPKKPESCTYLLTKLELSLMDNIKDD 387

  Fly   429 THFVQEMVNEQSVFCLPGSCFEYPGYVRIVLTVPGAMIEEACSRIAEFCDRHYKK 483
            ..|..::..|:::..|||.......::||.:.|...|:|:|..|:..||.||.||
plant   388 IDFCVKLAREENLVFLPGDALGLKNWMRITIGVEAHMLEDALERLKGFCTRHAKK 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1461	NP_001285238.1	tyr_amTase_E	79..481	CDD:273529	126/406 (31%)
CG1461	NP_001285238.1	AAT_like	112..475	CDD:99734	116/365 (32%)
SUR1	NP_179650.1	PLN02187	1..462	CDD:215119	137/445 (31%)
SUR1	NP_179650.1	AAT_like	69..433	CDD:99734	116/364 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	243	1.000	Domainoid score	I568
eggNOG	1	0.900	-	-		E1_COG0436
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	257	1.000	Inparanoid score	I991
OMA	1	1.010	-	-		QHG53692
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001879
OrthoInspector	1	1.000	-	-		otm2435
orthoMCL	1	0.900	-	-		OOG6_101502
Panther	1	1.100	-	-	O	PTHR45744
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1408
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.830