DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1461 and gpt

DIOPT Version :9

Sequence 1:	NP_001285238.1	Gene:	CG1461 / 32381	FlyBaseID:	FBgn0030558	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	XP_031759248.1	Gene:	gpt / 549559	XenbaseID:	XB-GENE-5824311	Length:	537	Species:	Xenopus tropicalis

Alignment Length:	472	Identity:	118/472 - (25%)
Similarity:	193/472 - (40%)	Gaps:	107/472 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 IRNIVESLKIKPNPEKP---MIPLSIGD-------PTTF---------------GNLKAADETMK 133
            ||.:....:::...:||   :|..:|||       |.||               .|....|...|
Frog    84 IRAVELEKELQQGVKKPFTEVIKANIGDAHAMGQKPITFLRQVSAICLYPELMNDNKFPEDVKQK 148

  Fly   134 A--VLHSLESGKYNGYASTQGHEIARKAVAKYSAHQRPDGEI--DANEVVLCSGCSSALEYCILA 194
            |  :|.:........|:::||.|:.|:.||||.  :|.||.|  |.|.:.|.:|.|.:: ..:|.
Frog   149 AARILQACGGHSIGAYSASQGIEVIRQDVAKYI--ERRDGGIQSDPNNIYLSTGASDSI-VTMLK 210

  Fly   195 LADRGQ-----NVLVPRPGFCLY-YTLAQGLDIEVRYYDLLPDQQWRADLVQLESLIDE-----N 248
            |...||     .||:|.|.:.|| ..||:...::|.|| |..:..|..|:.:|...:.|     :
Frog   211 LLVSGQGKSRTGVLIPIPQYPLYSAALAELNAVQVNYY-LDEENCWALDINELRRSLTEARKHCD 274

  Fly   249 TAALLINNPSNPCGSVFDEKHLRELIAICERHYLPIIADEIYEHFVFP---------------GS 298
            ...|.|.||.||.|.|...|.:.::|.......|.::|||:|:..|:.               |.
Frog   275 PKVLCIINPGNPTGQVQSRKCIEDVIRFAAEENLFLMADEVYQDNVYAKGCTFHSFKKVLFEMGP 339

  Fly   299 KHLAVSSLTTEVPVLSCGGLTKRFLVP-GWRMGWIIVHDRKNRLRDAIVGLKN--MCGRILGSNT 360
            |:      :..|.:.|....:|.::.. |:|.|::.|.:....::..:..|.:  :|..:.|.
Frog   340 KY------SETVELASFHSTSKGYMGECGFRGGYMEVINMDPAVKQQLTKLVSVRLCPPVPGQ-- 396

  Fly   361 IIQGALPDILTKTPQ----SY------FDGVIDVLHSNAMLAYKMLKQVRGL--DPVMPNGAMYM 413
                ||.|::...|:    ||      ...|:..|...|.|..::|.|..|:  :||  .||||.
Frog   397 ----ALLDVIVNPPKPGEPSYKQFMAEKQAVLGNLAEKARLTEEILNQSPGIRCNPV--QGAMYS 455

  Fly   414 MIGVSIERFPE----------FKDDTHFVQEMVNEQSVFCLPGSCF---EYPGYVRIVLTVPGAM 465
            ...:.|   ||          ...|..|..:::.|..:..:|||.|   |...:.|:.:..|...
Frog   456 FPRIHI---PEKAIKLAQAEGQAPDMFFCMKLLEETGICVVPGSGFGQREGTHHFRMTILPPTDK 517

  Fly   466 IEEACSRIAEFCDRHYK 482
            ::....|:.:|   |.|
Frog   518 LKSLLERLKDF---HQK 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1461	NP_001285238.1	tyr_amTase_E	79..481	CDD:273529	116/469 (25%)
CG1461	NP_001285238.1	AAT_like	112..475	CDD:99734	111/442 (25%)
gpt	XP_031759248.1	PTZ00377	58..537	CDD:240391	118/472 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910