DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1461 and tat

DIOPT Version :9

Sequence 1:	NP_001285238.1	Gene:	CG1461 / 32381	FlyBaseID:	FBgn0030558	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_001006790.1	Gene:	tat / 448486	XenbaseID:	XB-GENE-973688	Length:	456	Species:	Xenopus tropicalis

Alignment Length:	424	Identity:	220/424 - (51%)
Similarity:	294/424 - (69%)	Gaps:	15/424 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 WEIKGSKLSLNTHNRIRNIVESLKIKPNPEKPMIPLSIGDPTTFGNLKAADETMKAVLHSLESGK 143
            |.::.|::|..|.|.||.||:::...||||||||.|||||||.||||...:|.|||:..:::|.|
Frog    42 WAVRASEMSKKTFNPIRAIVDNMTAIPNPEKPMIALSIGDPTVFGNLPTDNEVMKAMKEAIDSKK 106

  Fly   144 YNGYASTQGHEIARKAVAKYSAHQRPDGEIDANEVVLCSGCSSALEYCILALADRGQNVLVPRPG 208
            |||||.:.|:..:|:.||||  :..|:..::|.:|:|.||||.|:|..:..||:.|||:||||||
Frog   107 YNGYAPSIGYLSSREVVAKY--YTCPEATLEAKDVILTSGCSQAIELALAVLANPGQNILVPRPG 169

  Fly   209 FCLYYTLAQGLDIEVRYYDLLPDQQWRADLVQLESLIDENTAALLINNPSNPCGSVFDEKHLREL 273
            |.||.|||..|.|||:.|:|||::.|..||..:|||:|:.||.::||||||||||||..|||:::
Frog   170 FSLYKTLALSLGIEVKLYNLLPEKSWEIDLTHMESLVDDKTACIIINNPSNPCGSVFSRKHLQKI 234

  Fly   274 IAICERHYLPIIADEIYEHFVFPGSKHLAVSSLTTEVPVLSCGGLTKRFLVPGWRMGWIIVHDRK 338
            :::..|..:||:|||||...||......|::.|::.||:||||||.||:||||||:|||::||||
Frog   235 LSVASRQCVPILADEIYGDMVFEEGAFQALAPLSSNVPILSCGGLAKRWLVPGWRLGWILIHDRK 299

  Fly   339 ----NRLRDAIVGLKNMCGRILGSNTIIQGALPDILTKTPQSYFDGVIDVLHSNAMLAYKMLKQV 399
                ..:|:.:|.|..   ||||..:|:||||..|:.||||.::|..|....|||.|.|..|..|
Frog   300 EIFGKEIREGLVRLSQ---RILGPCSIVQGALEHIMNKTPQEFYDNTISFTKSNADLCYTTLSSV 361

  Fly   400 RGLDPVMPNGAMYMMIGVSIERFPEFKDDTHFVQEMVNEQSVFCLPGSCFEYPGYVRIVLTVPGA 464
            .||.||.|.||||:|:|:.:|.||||:.|..|.:.|::||||||||.:|||||.|.|||||||..
Frog   362 PGLCPVRPAGAMYLMVGIEMEHFPEFESDVDFTERMISEQSVFCLPATCFEYPNYFRIVLTVPEE 426

  Fly   465 MIEEACSRIAEFCDRHYK-KESRNFIEHGLLDCD 497
            |:.|||.||.|:|:.||: .||...:|     ||
Frog   427 MMIEACRRIREYCESHYQGAESTQDLE-----CD 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1461	NP_001285238.1	tyr_amTase_E	79..481	CDD:273529	213/405 (53%)
CG1461	NP_001285238.1	AAT_like	112..475	CDD:99734	195/366 (53%)
tat	NP_001006790.1	TAT_ubiq	3..41	CDD:369474
tat	NP_001006790.1	tyr_amTase_E	42..443	CDD:273529	213/405 (53%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	408	1.000	Domainoid score	I690
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37293
Inparanoid	1	1.050	450	1.000	Inparanoid score	I1578
OMA	1	1.010	-	-		QHG53692
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001879
OrthoInspector	1	1.000	-	-		oto105466
Panther	1	1.100	-	-	LDO	PTHR45744
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1408
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.070