DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1461 and gpt

DIOPT Version :9

Sequence 1:	NP_001285238.1	Gene:	CG1461 / 32381	FlyBaseID:	FBgn0030558	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	XP_017213488.1	Gene:	gpt / 403086	ZFINID:	ZDB-GENE-050302-11	Length:	549	Species:	Danio rerio

Alignment Length:	555	Identity:	126/555 - (22%)
Similarity:	232/555 - (41%)	Gaps:	105/555 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 RNRASCTSRSPSEPE-----SPAP--VTPNCDVVDQALAELQLQSQDIRK-----QQDLVDTTAT 69
            |..|:..:..|..|:     ||.|  .:|:.|......|:.:...|.:.:     :|..|.|..|
Zfish    14 RCEAAYAAAYPKVPDWVLNFSPLPSLSSPHRDFSAFPAAQSEHMQQKMSENGAIPRQGKVLTVDT 78

  Fly    70 SSSSRKRSGWEIKGSKLSLNTHNRIRNIVESLKIKPNPEKP---MIPLSIGD-------PTTF-- 122
            .:::.|:..:.::|..:.       |.:....::|...:||   :|..:|||       |.||
Zfish    79 MNANVKKVDYAVRGPIVQ-------RAVQIEKELKEGVKKPFDEVIKANIGDAHAMGQRPITFFR 136

  Fly   123 -------------GNLKAADETMKA--VLHSLESGKYNGYASTQGHEIARKAVAKYSAHQRPDGE 172
                         .|....|...:|  :|.|........|.::||.:..|:.||||.  :|.||.
Zfish   137 QVMALCTYPQLLDDNKFPEDAKNRARRILQSCGGNSIGAYTTSQGIDCVRQDVAKYI--ERRDGG 199

  Fly   173 I--DANEVVLCSGCSSALEYCILALADRGQ-----NVLVPRPGFCLY-YTLAQGLDIEVRYYDLL 229
            |  |.:.:.|.:|.|..: ..||.|...|:     .|::..|.:.|| .::|:...:::.|| |.
Zfish   200 IPSDPDNIYLTTGASDGI-VTILKLLTAGEGLTRTGVMISIPQYPLYSASIAELGAVQINYY-LN 262

  Fly   230 PDQQWRADLVQLESLIDE-----NTAALLINNPSNPCGSVFDEKHLRELIAICERHYLPIIADEI 289
            .::.|..|:.:|:..:..     |...|.|.||.||.|.|...:.:.::|....:..|.::|||:
Zfish   263 EEKCWSLDISELQRSLQAARKHCNPRVLCIINPGNPTGQVQSRQCIEDVIQFAAKENLFLMADEV 327

  Fly   290 YEHFVF-PGSKHLAVSSLTTE--------VPVLSCGGLTKRFLVP-GWRMGWIIVHDRKNRLRDA 344
            |:..|: .|.:..:...:..|        |.:.|....:|.::.. |:|.|::.|.:....::..
Zfish   328 YQDNVYAKGCEFHSFKKVLFEMGPEYSKKVELASFHSTSKCYMGECGFRGGYMEVINMDADVKAQ 392

  Fly   345 IVGLKN--MCGRILGSNTIIQGALPDILTKTP-------QSYFD---GVIDVLHSNAMLAYKMLK 397
            :..|.:  :|....|.      ||.|::...|       |::..   .|:..|...|.|..::|.
Zfish   393 LTKLVSVRLCPPAPGQ------ALMDLVVNPPQPGEPSHQTFMQERTAVLSALAEKAKLTEQILN 451

  Fly   398 QVRGL--DPVMPNGAMYMMIGVSI-ER-FPEFK-----DDTHFVQEMVNEQSVFCLPGSCF---E 450
            .|.|:  :||  .||||....::: || ..|.|     .|..:..:::.|..:..:|||.|   |
Zfish   452 TVPGISCNPV--QGAMYSFPRITLPERAISEAKAKGQAPDMFYCMKLLEETGICLVPGSGFGQRE 514

  Fly   451 YPGYVRIVLTVPGAMIEEACSRIAEFCDRHYKKES 485
            ...:.|:.:..|...::...:::.:|..|..::.|
Zfish   515 GTYHFRMTILPPTDKLKLMLNKLKDFHQRFTQQYS 549

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1461	NP_001285238.1	tyr_amTase_E	79..481	CDD:273529	109/475 (23%)
CG1461	NP_001285238.1	AAT_like	112..475	CDD:99734	102/433 (24%)
gpt	XP_017213488.1	PTZ00377	70..549	CDD:240391	114/497 (23%)
gpt	XP_017213488.1	AAT_like	176..528	CDD:99734	90/363 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0436
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810