DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG1461 and Accs

DIOPT Version :9

Sequence 1:NP_001285238.1 Gene:CG1461 / 32381 FlyBaseID:FBgn0030558 Length:501 Species:Drosophila melanogaster
Sequence 2:NP_001277711.1 Gene:Accs / 329470 MGIID:1919717 Length:502 Species:Mus musculus


Alignment Length:489 Identity:105/489 - (21%)
Similarity:190/489 - (38%) Gaps:119/489 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    59 KQQDLVDTTATSSSSRK--RSGWEIKGSKLSLNTHNRIRNIVESLKIKPNPEKPMIPLSIGDPT- 120
            :|:....||.|.|:|.:  .||:   |..|.          .|.|: ||:..:|.: ..:|||| 
Mouse     6 QQESTAPTTCTGSASTQDMDSGY---GDGLQ----------GECLR-KPDQTQPKL-YGVGDPTA 55

  Fly   121 TFGN----LKAADETMKAVLHSLESG-------KYN----------------------------- 145
            ||.:    |.:....:|....|.|.|       :|:                             
Mouse    56 TFSSDSSCLSSRGRVIKWFWDSAEEGYRTYHMDEYDEDKNPSGIINLGTSENKLCFDLLSWRLTQ 120

  Fly   146 -----------GYASTQGHEIARKAVAKY-SAHQRPDGEIDANEVVLCSGCSSALEYCILALADR 198
                       .|...:||...|:.|||: |.:.:....:....||:.:||:|........|.:.
Mouse   121 GDMLHVEPSLLQYPDWRGHLFLREEVAKFLSFYCKSPAPLKPENVVVLNGCASLFSALATVLCEA 185

  Fly   199 GQNVLVPRPGFCLYY-TLAQGL----DIEVRYYDL------LPDQQWRADLVQLESLID------ 246
            |:.:|:|.|    || .:.|.:    ::.:.|..|      |..:.::..:.:||.::.      
Mouse   186 GEALLIPTP----YYGAITQHIYLYGNVRLAYVYLDSKVTGLNTRPFQLTVEKLEMVLQGVSSEG 246

  Fly   247 ENTAALLINNPSNPCGSVFDEKHLRELIAICERHYLPIIADEIYEHFVFPGS----KHLAVSSLT 307
            .....|::.||.||.|.|:..:.|::.:....||.|.:|.||:|...||..|    ..|::..|.
Mouse   247 VKVKGLILINPQNPLGDVYSPEELQDFLRFAMRHKLHVIMDEVYMLSVFEESLGYRSVLSLERLP 311

  Fly   308 TEVPVLSCGGLTKRFLVPGWRMGWIIVHDRKNRLRDAIVGLKNMCGRILGSNTIIQGALPDILTK 372
            ...........:|.|.:.|.|.|  :::.....:..|:..|   | |..|.:.::|..:..:|..
Mouse   312 DPQRTHVMWATSKDFGMSGLRFG--VLYTENQHVATAVASL---C-RYHGLSGLVQHQMAQLLRD 370

  Fly   373 TPQSYFDGVIDVL----HSNAMLAYKML-KQVRGLD-PVMPNGAMYMMIGVSIERF---PEFKDD 428
                 .|.:..|.    |:....|:..: :::|.|. |.:..||.: .|.|.:.::   ..|:::
Mouse   371 -----HDWISQVYLPENHARLKAAHTYVSEELRALGIPFVSRGAGF-FIWVDLRKYLCKGTFEEE 429

  Fly   429 THFVQEMVNEQSVFCLPGSCFE--YPGYVRIVLT 460
            ....::.: :..|....|..||  .||:.|:|.:
Mouse   430 ALLWRQFL-DNKVLLSSGKTFECKEPGWFRVVFS 462

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1461NP_001285238.1 tyr_amTase_E 79..481 CDD:273529 97/467 (21%)
AAT_like 112..475 CDD:99734 90/434 (21%)
AccsNP_001277711.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..24 6/17 (35%)
PLN02450 81..483 CDD:178069 80/399 (20%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0436
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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