DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG1461 and Gpt2

DIOPT Version :9

Sequence 1:NP_001285238.1 Gene:CG1461 / 32381 FlyBaseID:FBgn0030558 Length:501 Species:Drosophila melanogaster
Sequence 2:NP_001012057.1 Gene:Gpt2 / 307759 RGDID:1305462 Length:522 Species:Rattus norvegicus


Alignment Length:546 Identity:120/546 - (21%)
Similarity:221/546 - (40%) Gaps:103/546 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    19 RASCTSRSPSEPESPAP-VTPNCDVVDQALAELQLQSQDIRKQQDLVDTTATSSSSRKRSGWEIK 82
            ||:...|..|.|.:..| ...:.....:|.|.|:::.:  |..:|.:.|..:.:...|...:.::
  Rat     3 RAAVLVRRGSCPRASGPWGRSHSSAAAEASAALKVRPE--RSPRDRILTLESMNPQVKAVEYAVR 65

  Fly    83 G------SKLSLNTHNRIRNIVESLKIKPNPEKPMIPLSIGD-------PTTF----------GN 124
            |      .::.:.....|:        ||..|  :|..:|||       |.||          .|
  Rat    66 GPIVLKAGEIEMELQRGIK--------KPFTE--VIRANIGDAHAMGQQPITFLRQVMALCTYPN 120

  Fly   125 L-------KAADETMKAVLHSLESGKYNGYASTQGHEIARKAVAKYSAHQRPDG-EIDANEVVLC 181
            |       :.|.:..:.:|.:........|:::||....|:.||.:..  |.|| ..|.:.:.|.
  Rat   121 LLNSPSFPEDAKKRARRILQACGGNSLGSYSASQGVNCIREDVAAFIT--RRDGVPADPDNIYLT 183

  Fly   182 SGCSSALEYCILALADRG----QNVLVPRPGFCLYYTLAQGLD-IEVRYYDLLPDQQWRADLVQL 241
            :|.|..:...:..|...|    ..|::|.|.:.||..:...|| |:|.|| |..|..|..::.:|
  Rat   184 TGASDGISTILKLLVSGGGKSRTGVMIPIPQYPLYSAVISELDAIQVNYY-LDEDNCWALNVDEL 247

  Fly   242 ESLIDE-----NTAALLINNPSNPCGSVFDEKHLRELIAICERHYLPIIADEIYEHFVF-PGSKH 300
            ...:.:     :...|.|.||.||.|.|...|.:.::|.......|.::|||:|:..|: |..:.
  Rat   248 RRALRQAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADEVYQDNVYSPDCRF 312

  Fly   301 LAVSSL--------TTEVPVLSCGGLTKRFLVP-GWRMGWIIVHDRKNRLRDAIVGLKN--MCGR 354
            .:...:        ::.|.:.|....:|.::.. |:|.|::.|.:....::..:|.|.:  :|..
  Rat   313 HSFKKVLYQMGPEYSSNVELASFHSTSKGYMGECGYRGGYMEVINLHPEIKGQLVKLLSVRLCPP 377

  Fly   355 ILGSNTIIQGALPDILTKTP----QSY------FDGVIDVLHSNAMLAYKMLKQVRGLDPVMPNG 409
            :.|     |.|: ||:...|    :|:      .:.|:..|...|.|...:..||.|:......|
  Rat   378 VSG-----QAAM-DIVVNPPVPGEESFEQFTREKESVLGNLAKKAKLTEDLFNQVPGIQCNPLQG 436

  Fly   410 AMY-----MMIGVSIERFPEFK--DDTHFVQEMVNEQSVFCLPGSCF---EYPGYVRIVLTVPGA 464
            |||     ::...::|.....|  .|..:..:::.|..:..:|||.|   |...:.|:.:..|..
  Rat   437 AMYAFPRILIPAKAVEAAQSHKMAPDMFYCMKLLEETGICVVPGSGFGQREGTYHFRMTILPPVE 501

  Fly   465 MIEEACSRIAEFCDRHYKKESRNFIE 490
            .::....::.:|   |.|     |:|
  Rat   502 KLKTVLHKVKDF---HLK-----FLE 519

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1461NP_001285238.1 tyr_amTase_E 79..481 CDD:273529 103/474 (22%)
AAT_like 112..475 CDD:99734 97/429 (23%)
Gpt2NP_001012057.1 PTZ00377 48..522 CDD:240391 109/499 (22%)
AAT_like 123..512 CDD:99734 88/397 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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