Protein Alignment Tat and Gpt2

DIOPT Version :10

• Sequence 1: NP_572953.1
• Gene: Tat / 32381
• FlyBaseID: FBgn0030558
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001012057.1
• Gene: Gpt2 / 307759
• RGDID: 1305462
• Length: 522
• Species: Rattus norvegicus
• Alignment Length: 546
• Identity: 120/546 - (21%)
• Similarity: 221/546 - (40%)
• Gaps: 103/546 - (18%)

  Fly    19 RASCTSRSPSEPESPAP-VTPNCDVVDQALAELQLQSQDIRKQQDLVDTTATSSSSRKRSGWEIK 82
            ||:...|..|.|.:..| ...:.....:|.|.|:::.:  |..:|.:.|..:.:...|...:.::
  Rat     3 RAAVLVRRGSCPRASGPWGRSHSSAAAEASAALKVRPE--RSPRDRILTLESMNPQVKAVEYAVR 65

  Fly    83 G------SKLSLNTHNRIRNIVESLKIKPNPEKPMIPLSIGD-------PTTF----------GN 124
            |      .::.:.....|:        ||..|  :|..:|||       |.||          .|
  Rat    66 GPIVLKAGEIEMELQRGIK--------KPFTE--VIRANIGDAHAMGQQPITFLRQVMALCTYPN 120

  Fly   125 L-------KAADETMKAVLHSLESGKYNGYASTQGHEIARKAVAKYSAHQRPDG-EIDANEVVLC 181
            |       :.|.:..:.:|.:........|:::||....|:.||.:..  |.|| ..|.:.:.|.
  Rat   121 LLNSPSFPEDAKKRARRILQACGGNSLGSYSASQGVNCIREDVAAFIT--RRDGVPADPDNIYLT 183

  Fly   182 SGCSSALEYCILALADRG----QNVLVPRPGFCLYYTLAQGLD-IEVRYYDLLPDQQWRADLVQL 241
            :|.|..:...:..|...|    ..|::|.|.:.||..:...|| |:|.|| |..|..|..::.:|
  Rat   184 TGASDGISTILKLLVSGGGKSRTGVMIPIPQYPLYSAVISELDAIQVNYY-LDEDNCWALNVDEL 247

  Fly   242 ESLIDE-----NTAALLINNPSNPCGSVFDEKHLRELIAICERHYLPIIADEIYEHFVF-PGSKH 300
            ...:.:     :...|.|.||.||.|.|...|.:.::|.......|.::|||:|:..|: |..:.
  Rat   248 RRALRQAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADEVYQDNVYSPDCRF 312

  Fly   301 LAVSSL--------TTEVPVLSCGGLTKRFLVP-GWRMGWIIVHDRKNRLRDAIVGLKN--MCGR 354
            .:...:        ::.|.:.|....:|.::.. |:|.|::.|.:....::..:|.|.:  :|..
  Rat   313 HSFKKVLYQMGPEYSSNVELASFHSTSKGYMGECGYRGGYMEVINLHPEIKGQLVKLLSVRLCPP 377

  Fly   355 ILGSNTIIQGALPDILTKTP----QSY------FDGVIDVLHSNAMLAYKMLKQVRGLDPVMPNG 409
            :.|     |.|: ||:...|    :|:      .:.|:..|...|.|...:..||.|:......|
  Rat   378 VSG-----QAAM-DIVVNPPVPGEESFEQFTREKESVLGNLAKKAKLTEDLFNQVPGIQCNPLQG 436

  Fly   410 AMY-----MMIGVSIERFPEFK--DDTHFVQEMVNEQSVFCLPGSCF---EYPGYVRIVLTVPGA 464
            |||     ::...::|.....|  .|..:..:::.|..:..:|||.|   |...:.|:.:..|..
  Rat   437 AMYAFPRILIPAKAVEAAQSHKMAPDMFYCMKLLEETGICVVPGSGFGQREGTYHFRMTILPPVE 501

  Fly   465 MIEEACSRIAEFCDRHYKKESRNFIE 490
            .::....::.:|   |.|     |:|
  Rat   502 KLKTVLHKVKDF---HLK-----FLE 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tat	NP_572953.1	tyr_amTase_E	79..481	CDD:273529	103/474 (22%)
Gpt2	NP_001012057.1	PTZ00377	48..522	CDD:240391	109/499 (22%)