Protein Alignment Tat and GPT

DIOPT Version :10

• Sequence 1: NP_572953.1
• Gene: Tat / 32381
• FlyBaseID: FBgn0030558
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_005300.1
• Gene: GPT / 2875
• HGNCID: 4552
• Length: 496
• Species: Homo sapiens
• Alignment Length: 499
• Identity: 116/499 - (23%)
• Similarity: 209/499 - (41%)
• Gaps: 103/499 - (20%)

  Fly    68 ATSSSSRK---RSGWEIKGSKLSLNTHN-RIRNIVESLK-------------IKPNPEKP---MI 112
            |:|:..|.   |.|  ::...|:|:..| |:|.:..:::             ::...:||   :|
Human     2 ASSTGDRSQAVRHG--LRAKVLTLDGMNPRVRRVEYAVRGPIVQRALELEQELRQGVKKPFTEVI 64

  Fly   113 PLSIGD-------PTTF--------------GNLKAADETMK---AVLHSLESGKYNGYASTQGH 153
            ..:|||       |.||              .:....|:..|   .:|.:........|:.:.|.
Human    65 RANIGDAQAMGQRPITFLRQVLALCVNPDLLSSPNFPDDAKKRAERILQACGGHSLGAYSVSSGI 129

  Fly   154 EIARKAVAKYSAHQRPDGEI--DANEVVLCSGCSSALEYCI-LALADRGQ---NVLVPRPGFCLY 212
            ::.|:.||:|.  :|.||.|  |.|.|.|.:|.|.|:...: |.:|..|.   .||:|.|.:.||
Human   130 QLIREDVARYI--ERRDGGIPADPNNVFLSTGASDAIVTVLKLLVAGEGHTRTGVLIPIPQYPLY 192

  Fly   213 -YTLAQGLDIEVRYYDLLPDQQWRADLVQLESLIDE-----NTAALLINNPSNPCGSVFDEKHLR 271
             .|||:...::|.|| |..::.|..|:.:|...:.:     ...||.:.||.||.|.|...:.:.
Human   193 SATLAELGAVQVDYY-LDEERAWALDVAELHRALGQARDHCRPRALCVINPGNPTGQVQTRECIE 256

  Fly   272 ELIAICERHYLPIIADEIYEHFVF-PGSKHLAVSSLTTEV--------PVLSCGGLTKRFLVP-G 326
            .:|.......|.::|||:|:..|: .||:..:...:..|:        .:.|....:|.::.. |
Human   257 AVIRFAFEERLFLLADEVYQDNVYAAGSQFHSFKKVLMEMGPPYAGQQELASFHSTSKGYMGECG 321

  Fly   327 WRMGWIIVHDRKNRLRDAIVGLKN--MCGRILGSNTIIQGALPDILTKTP----------QSYFD 379
            :|.|::.|.:....::..::.|.:  :|..:.|.      ||.|::...|          |:...
Human   322 FRGGYVEVVNMDAAVQQQMLKLMSVRLCPPVPGQ------ALLDLVVSPPAPTDPSFAQFQAEKQ 380

  Fly   380 GVIDVLHSNAMLAYKMLKQVRGL--DPVMPNGAMYMMIGV-----SIERFPE--FKDDTHFVQEM 435
            .|:..|.:.|.|..::..:..|:  :||  .||||....|     ::||..|  ...|..|...:
Human   381 AVLAELAAKAKLTEQVFNEAPGISCNPV--QGAMYSFPRVQLPPRAVERAQELGLAPDMFFCLRL 443

  Fly   436 VNEQSVFCLPGSCF---EYPGYVRIVLTVPGAMIEEACSRIAEF 476
            :.|..:..:|||.|   |...:.|:.:..|...:.....:::.|
Human   444 LEETGICVVPGSGFGQREGTYHFRMTILPPLEKLRLLLEKLSRF 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tat	NP_572953.1	tyr_amTase_E	79..481	CDD:273529	111/485 (23%)
GPT	NP_005300.1	PTZ00377	17..496	CDD:240391	111/482 (23%)