DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1461 and C32F10.8

DIOPT Version :9

Sequence 1:	NP_001285238.1	Gene:	CG1461 / 32381	FlyBaseID:	FBgn0030558	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_001359801.1	Gene:	C32F10.8 / 172252	WormBaseID:	WBGene00016333	Length:	504	Species:	Caenorhabditis elegans

Alignment Length:	517	Identity:	123/517 - (23%)
Similarity:	201/517 - (38%)	Gaps:	125/517 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 LVDTTATSSSSRKRSGWEIKGSKLSLNTHNRIRNIVE----------------SLKIKPNPEKP- 110
            ||.:....:|:|      |..|..:|||.|...|:::                ..::....:||
Worm    10 LVTSRFFGTSTR------IMASGKTLNTSNINPNVIKMEYAVRGPIVIRAVELEKELATGAQKPF 68

  Fly   111 --MIPLSIGD-------PTTFGNLKAA----DETMK--------------AVLHSLESGKYNGYA 148
              :|..:|||       |.||.....|    .|.||              |.|.|........|:
Worm    69 PNVIKANIGDAHAMGQKPITFIRQLLACIVNPEIMKTDKSIPSDVIEHANAFLGSCGGKSAGAYS 133

  Fly   149 STQGHEIARKAVAKYSAHQRPDGEIDAN--EVVLCSGCSSALEYCILALADRGQN-----VLVPR 206
            .:.|.||.||.||:|.  :|.||.|..|  :|.|..|.|.::.. :|.|.....|     |::|.
Worm   134 QSTGVEIVRKHVAEYI--KRRDGGIPCNSEDVCLSGGASESIRN-VLKLFINHNNAKKVGVMIPI 195

  Fly   207 PGFCLYYTLAQGLDI-EVRYYDLLPDQQWRADLVQLESLIDE-----NTAALLINNPSNPCGSVF 265
            |.:.||....:...: :|.|| |.....|..|..:||...::     :...|.|.||.||.|...
Worm   196 PQYPLYSATIEEFGLGQVGYY-LSESSNWSMDEAELERSFNDHCKEYDIRVLCIINPGNPTGQAL 259

  Fly   266 DEKHLRELIAICERHYLPIIADEIYEHFVF-PGSKHLAVSSLTTE-------VPVLSCGGLTKRF 322
            ..:::..:|...::..|.::|||:|:..|: .||:..:...:..|       :.:.|...::|.:
Worm   260 SRENIETIIKFAQKKNLFLMADEVYQDNVYAQGSQFHSFKKVLVEMGEPYNKMELASFHSVSKGY 324

  Fly   323 LVP-GWRMGWIIVHDRKNRLRDAIVGLKNM-----CGRILGSNTIIQGALPDILTKTPQ----SY 377
            :.. |.|.|::   :..|...:..|..|.|     |..:||.      |:.|.:...|:    ||
Worm   325 MGECGMRGGYV---EFLNLDPEVYVLFKKMISAKLCSTVLGQ------AVIDAVVNPPKEGDASY 380

  Fly   378 F------DGVIDVLHSNAMLAYKMLKQVRGL--DPVMPNGAMYMMIGV-----------SIERFP 423
            .      |.|:..|...|.|..|....:.|:  :||  .||||....:           |:.:.|
Worm   381 ALWKQEKDAVLASLKERATLVEKAYSSIDGISCNPV--QGAMYAFPQITIPQRAVEKAQSLNQQP 443

  Fly   424 EFKDDTHFVQEMVNEQSVFCLPGSCF-EYPG--YVRIVLTVPGAMIEEACSRIAEFCDRHYK 482
            :|    .:..:::....:..:|||.| :..|  :.|..:.....:.::..||   |.|.|.|
Worm   444 DF----FYAMQLLETTGICIVPGSGFGQKDGTYHFRTTILPQPELFKDMLSR---FTDFHQK 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1461	NP_001285238.1	tyr_amTase_E	79..481	CDD:273529	117/498 (23%)
CG1461	NP_001285238.1	AAT_like	112..475	CDD:99734	106/440 (24%)
C32F10.8	NP_001359801.1	PTZ00377	25..504	CDD:240391	118/496 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910