DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1461 and Gpt2

DIOPT Version :9

Sequence 1:	NP_001285238.1	Gene:	CG1461 / 32381	FlyBaseID:	FBgn0030558	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_776291.1	Gene:	Gpt2 / 108682	MGIID:	1915391	Length:	522	Species:	Mus musculus

Alignment Length:	546	Identity:	117/546 - (21%)
Similarity:	219/546 - (40%)	Gaps:	103/546 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 RASCTSRSPSEPESPAP-VTPNCDVVDQALAELQLQSQDIRKQQDLVDTTATSSSSRKRSGWEIK 82
            ||:...|..|.|.:..| ...:.....:|.|.|:::.:  |..:|.:.|..:.:...|...:.::
Mouse     3 RAAVLVRRGSCPRASGPWGRSHSSAAAEASAALKVRPE--RSPRDRILTLESMNPQVKAVEYAVR 65

  Fly    83 G------SKLSLNTHNRIRNIVESLKIKPNPEKPMIPLSIGD-------PTTF----------GN 124
            |      .::.:.....|:        ||..|  :|..:|||       |.||          .|
Mouse    66 GPIVLKAGEIEMELQRGIK--------KPFTE--VIRANIGDAHAMGQQPITFLRQVMALCTYPN 120

  Fly   125 L-------KAADETMKAVLHSLESGKYNGYASTQGHEIARKAVAKYSAHQRPDG-EIDANEVVLC 181
            |       :.|.:..:.:|.:........|:::||....|:.||.:..  |.|| ..|.:.:.|.
Mouse   121 LLNSPSFPEDAKKRARRILQACGGNSLGSYSASQGVNCIREDVAAFIT--RRDGVPADPDNIYLT 183

  Fly   182 SGCSSALEYCILALADRG----QNVLVPRPGFCLYYTLAQGLD-IEVRYYDLLPDQQWRADLVQL 241
            :|.|..:...:..|...|    ..|::|.|.:.||..:...|| ::|.|| |..:..|..::.:|
Mouse   184 TGASDGISTILKLLVSGGGKSRTGVMIPIPQYPLYSAVISELDAVQVNYY-LDEENCWALNVDEL 247

  Fly   242 ESLIDE-----NTAALLINNPSNPCGSVFDEKHLRELIAICERHYLPIIADEIYEHFVF-PGSKH 300
            ...:.:     :...|.|.||.||.|.|...|.:.::|.......|.::|||:|:..|: |..:.
Mouse   248 RRALRQAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADEVYQDNVYSPDCRF 312

  Fly   301 LAVSSL--------TTEVPVLSCGGLTKRFLVP-GWRMGWIIVHDRKNRLRDAIVGLKN--MCGR 354
            .:...:        ::.|.:.|....:|.::.. |:|.|::.|.:....::..:|.|.:  :|..
Mouse   313 HSFKKVLYQMGHEYSSNVELASFHSTSKGYMGECGYRGGYMEVINLHPEIKGQLVKLLSVRLCPP 377

  Fly   355 ILGSNTIIQGALPDILTKTPQSYFDG----------VIDVLHSNAMLAYKMLKQVRGLDPVMPNG 409
            :.|     |.|: ||:...|:...:.          |:..|...|.|...:..||.|:......|
Mouse   378 VSG-----QAAM-DIVVNPPEPGEESFEQFSREKEFVLGNLAKKAKLTEDLFNQVPGIQCNPLQG 436

  Fly   410 AMY-----MMIGVSIERFPEFK--DDTHFVQEMVNEQSVFCLPGSCF---EYPGYVRIVLTVPGA 464
            |||     ::...::|.....|  .|..:..:::.|..:..:|||.|   |...:.|:.:..|..
Mouse   437 AMYAFPRILIPAKAVEAAQSHKMAPDMFYCMKLLEETGICVVPGSGFGQREGTYHFRMTILPPVD 501

  Fly   465 MIEEACSRIAEFCDRHYKKESRNFIE 490
            .::....::.:|   |.|     |:|
Mouse   502 KLKTVLHKVKDF---HLK-----FLE 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1461	NP_001285238.1	tyr_amTase_E	79..481	CDD:273529	100/474 (21%)
CG1461	NP_001285238.1	AAT_like	112..475	CDD:99734	94/429 (22%)
Gpt2	NP_776291.1	PTZ00377	48..522	CDD:240391	106/499 (21%)
Gpt2	NP_776291.1	AAT_like	123..512	CDD:99734	85/397 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0436
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810