Protein Alignment HOXD12 and Dr

DIOPT Version :10

• Sequence 1: NP_067016.3
• Gene: HOXD12 / 3238
• HGNCID: 5135
• Length: 270
• Species: Homo sapiens
• Sequence 2: NP_477324.1
• Gene: Dr / 45285
• FlyBaseID: FBgn0000492
• Length: 515
• Species: Drosophila melanogaster
• Alignment Length: 193
• Identity: 61/193 - (31%)
• Similarity: 81/193 - (41%)
• Gaps: 43/193 - (22%)

Human    77 LAGSGPLGLQPPTAKDGPEEQAKFYAPEAAAGPEERGRT--RPSFAPESSLAPAVAALKAAKYDY 139
            |.|||.....|.....|...|:...:|.|.|.    |..  ||:  |.|:||.|..|       :
  Fly   321 LDGSGKSLESPHGPPPGSHMQSTILSPAALAS----GHVPIRPT--PFSALAAAAVA-------W 372

Human   140 AGVGRATPGSTTLLQGAPCAP-------GFKDDTKGPLNLNMTVQAAGVASCLRPSLPDGLPWGA 197
            .|:|...|...| .|..|..|       ||..|...|..:...         ||...|:
  Fly   373 TGMGGGVPWPGT-RQMPPFGPPGMFPGAGFGGDANEPPRIKCN---------LRKHKPN------ 421

Human   198 APGRARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKIWFQNRRMKKKRV 260
                 ||.|.|:|.||:..||.:|...::::..:|.|.|:.|.|::.||||||||||.|.||:
  Fly   422 -----RKPRTPFTTQQLLSLEKKFREKQYLSIAERAEFSSSLRLTETQVKIWFQNRRAKAKRL 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXD12	NP_067016.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	102..122		6/21 (29%)
		Homeodomain	203..259	CDD:459649	26/55 (47%)
Dr	NP_477324.1	Homeodomain	422..478	CDD:459649	26/55 (47%)